In: Cellular and Molecular Bioengineering, 2015, vol. 8, no. 1, p. 160-177
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In: Advanced Functional Materials, 2020, p. 2002630
Nanoparticle adsorption to substrates pose a unique challenge to understand uptake mechanisms as it involves the organization of complex cytoskeletal components by cells to perform endocytosis/phagocytosis. In particular, it is not well‐understood from a cell mechanics perspective how the adhesion of particles on substrate will influence the ease of material clearance. By using a particle...
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In: mBio, 2020, vol. 11, no. 2, p. -
The opportunistic bacterium Pseudomonas aeruginosa produces the fucose- specific lectin LecB, which has been identified as a virulence factor. LecB has a tetrameric structure with four opposing binding sites and has been shown to act as a cross-linker. Here, we demonstrate that LecB strongly binds to the glycosylated moieties of β1-integrins on the basolateral plasma membrane of epithelial...
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In: Evolution Letters, 2020, vol. 4, no. 2, p. 94–108
Evolutionary processes, including selection, can be indirectly inferred based on patterns of genomic variation among contemporary populations or species. However, this often requires unrealistic assumptions of ancestral demography and selective regimes. Sequencing ancient DNA from temporally spaced samples can inform about past selection processes, as time series data allow direct...
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In: Cancer and Metastasis Reviews, 2014, vol. 33, no. 1, p. 87-100
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In: Cellular and Molecular Life Sciences, 2018, vol. 75, no. 24, p. 4643–4666
The Ca2+-binding protein parvalbumin (PV) and mitochondria play important roles in Ca2+ signaling, buffering and sequestration. Antagonistic regulation of PV and mitochondrial volume is observed in in vitro and in vivo model systems. Changes in mitochondrial morphology, mitochondrial volume and dynamics (fusion, fission, mitophagy) resulting from modulation of PV were investigated in MDCK...
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In: The AAPS Journal, 2008, vol. 10, no. 2, p. 349-359
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In: Pharmaceutical Research, 2004, vol. 21, no. 1, p. 33-42
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In: Cell Biology and Toxicology, 2013, vol. 29, no. 1, p. 39-58
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In: Molecular Neurobiology, 2006, vol. 34, no. 1, p. 67-80
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