Université de Fribourg

Clostridium chauvoei, an evolutionary dead-end pathogen

Rychener, Lorenz ; In-Albon, Saria ; Djordjevic, Steven P. ; Nicholson, Pamela ; Chowdhury, Piklu Roy ; Ziech, Rosangela E. ; Vargas, Agueda C. de ; Frey, Joachim ; Falquet, Laurent

In: Frontiers in Microbiology, 2017, vol. 8, p. -

Full genome sequences of 20 strains of Clostridium chauvoei, the etiological agent of blackleg of cattle and sheep, isolated from four different continents over a period of 64 years (1951–2015) were determined and analyzed. The study reveals that the genome of the species C. chauvoei is highly homogeneous compared to the closely related species C. perfringens, a widespread pathogen that...