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Targeting the DNA damage response for patients with lymphoma : preclinical and clinical evidences

Carrassa, Laura ; Colombo, Ilaria ; Damia, Giovanna ; Bertoni, Francesco

In: Cancer treatment reviews, 2020, vol. 90, p. 11

The DNA damage response (DDR) is a well-coordinated cellular network activated by DNA damage. The unravelling of the key players in DDR, their specific inactivation in different tumor types and the synthesis of specific chemical inhibitors of DDR represent a new hot topic in cancer therapy. In this article, we will review the importance of DDR in lymphoma development and how this can be...

Personal or first-degree family breast cancer history: which has higher impact on tumor detection and tumor size in breast cancer

Schwab, Fabienne ; Kilic, Nerbil ; Huang, Dorothy ; Schmid, Seraina ; Vetter, Marcus ; Schötzau, Andreas ; Güth, Uwe

In: Archives of Gynecology and Obstetrics, 2015, vol. 291, no. 6, p. 1387-1394

Changes in autopsy rates among cancer patients and their impact on cancer statistics from a public health point of view: a longitudinal study from 1980 to 2010 with data from Cancer Registry Zurich

Bieri, Uwe ; Moch, Holger ; Dehler, Silvia ; Korol, Dimitri ; Rohrmann, Sabine

In: Virchows Archiv, 2015, vol. 466, no. 6, p. 637-643

Associations between objective and self-reported physical activity and vitamin D serum levels in the US population

Wanner, Miriam ; Richard, Aline ; Martin, Brian ; Linseisen, Jakob ; Rohrmann, Sabine

In: Cancer Causes & Control, 2015, vol. 26, no. 6, p. 881-891

Survival After Surgical Drainage of Malignant Pericardial Effusion

Niclauss, Lars ; Montemurro, Michael ; Prêtre, René

In: World Journal of Surgery, 2015, vol. 39, no. 7, p. 1767-1772

Mediterranean diet and mortality in Switzerland: an alpine paradox?

Vormund, Kerstin ; Braun, Julia ; Rohrmann, Sabine ; Bopp, Matthias ; Ballmer, Peter ; Faeh, David

In: European Journal of Nutrition, 2015, vol. 54, no. 1, p. 139-148

Socio-economic trajectories and cardiovascular disease mortality in older people: the English Longitudinal Study of Ageing

Stringhini, Silvia ; Zaninotto, Paola ; Kumari, Meena ; Kivimäki, Mika ; Lassale, Camille ; Batty, G David

In: International Journal of Epidemiology, 2018, vol. 47, no. 1, p. 36-46

Effectiveness of an additional individualized multi-component complementary medicine treatment on health-related quality of life in breast cancer patients: a pragmatic randomized trial

Witt, Claudia ; Außerer, Oskar ; Baier, Susanne ; Heidegger, Herbert ; Icke, Katja ; Mayr, Oswald ; Mitterer, Manfred ; Roll, Stephanie ; Spizzo, Gilbert ; Scherer, Arthur ; Thuile, Christian ; Wieser, Anton ; Schützler, Lena

In: Breast Cancer Research and Treatment, 2015, vol. 149, no. 2, p. 449-460

Breast cancer and pregnancy

Knabben, Laura ; Mueller, Michel D.

In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -

Retinoic acid sensitivity of triple-negative breast cancer cells characterized by constitutive activation of the NOTCH1 pathway : the role of RARβ

Paroni, Gabriela ; Zanetti, Adriana ; Barzago, Maria Monica ; Kurosaki, Mami ; Guarrera, Luca ; Fratelli, Maddalena ; Troiani, Martina ; Ubezio, Paolo ; Bolis, Marco ; Vallerga, Arianna ; Biancardi, Federica ; Terao, Mineko ; Garattini, Enrico

In: Cancers, 2020, vol. 12, no. 10, p. 23 p

Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks effective therapeutic options. In this study, we profile eighteen TNBC cell lines for their sensitivity to the anti-proliferative action of all-trans retinoic acid (ATRA). The only three cell lines (HCC-1599, MB- 157 and MDA-MB-157) endowed with ATRA-sensitivity are characterized by genetic aberrations of the NOTCH1-gene,...