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From zero to six double bonds: phospholipid unsaturation and organelle function

Antonny, Bruno ; Vanni, Stefano ; Shindou, Hideo ; Thierry, Ferreira

In: Trends in Cell Biology, 2015, vol. 25, no. 7, p. 427–436

Cellular phospholipids (PLs) differ by the nature of their polar heads as well as by the length and unsaturation level of their fatty acyl chains. We discuss how the ratio between saturated, monounsaturated, and polyunsaturated PLs impacts on the functions of such organelles as the endoplasmic reticulum, synaptic vesicles, and photoreceptor discs. Recent experiments and simulations suggest...

Effects of anti-PD-1 immunotherapy on tumor regression: insights from a patient-derived xenograft model

Martín-Ruiz, Asunción ; Fiuza-Luces, Carmen ; Martínez-Martínez, Esther ; Arias, Clemente F. ; Gutiérrez, Lourdes ; Ramírez, Manuel ; Martín-Acosta, Paloma ; Coronado, Maria José ; Lucia, Alejandro ; Provencio, Mariano

In: Scientific Reports, 2020, vol. 10, no. 1, p. 7078

Immunotherapies, such as checkpoint blockade of programmed cell death protein-1 (PD-1), have resulted in unprecedented improvements in survival for patients with lung cancer. Nonetheless, not all patients benefit equally and many issues remain unresolved, including the mechanisms of action and the possible effector function of immune cells from non-lymphoid lineages. The purpose of this...

Reconstructing medieval April-July mean temperatures in East Anglia, 1256-1431

Pribyl, Kathleen ; Cornes, Richard ; Pfister, Christian

In: Climatic Change, 2012, vol. 113, no. 2, p. 393-412

The role of α-tocopherol inpreventing disease

Azzi, Angelo

In: European Journal of Nutrition, 2004, vol. 43, p. i18-i25

Enhancing numerical constraint propagation using multiple inclusion representations

Vu, Xuan-Ha ; Sam-Haroud, Djamila ; Faltings, Boi

In: Annals of Mathematics and Artificial Intelligence, 2009, vol. 55, no. 3-4, p. 295-354

Effects of sample handling and storage on quantitative lipid analysis in human serum

Zivkovic, Angela ; Wiest, Michelle ; Nguyen, Uyen ; Davis, Ryan ; Watkins, Steven ; German, J.

In: Metabolomics, 2009, vol. 5, no. 4, p. 507-516

Determination of digestible energy values and fermentabilities of dietary fibre supplements: a European interlaboratory study in vivo

Livesey, G. ; Smith, T. ; Eggum, B. O. ; Tetens, I. H. ; Nyman, M. ; Roberfroid, M. ; Delzenne, N. ; Schweizer, T. F. ; Decombaz, J.

In: British Journal of Nutrition, 1995, vol. 74, no. 3, p. 289-302

Coconut fat and serum lipoproteins: effects of partial replacement with unsaturated fats

Mendis, Shanthi ; Samarajeewa, U. ; Thattil, R. O.

In: British Journal of Nutrition, 2001, vol. 85, no. 5, p. 583-589

Starch mobilization in leaves

Smith, Alison M. ; Zeeman, Samuel C. ; Thorneycroft, David ; Smith, Steven M.

In: Journal of Experimental Botany, 2003, vol. 54, no. 382, p. 577-583

Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease

Wright, Anthony J. A. ; Southon, Susan ; Chopra, Mridula ; Meyer-Wenger, Anita ; Moser, Ulrich ; Granado, Fernando ; Olmedilla, Begoña ; Corridan, Bernice ; Hinninger, Isabelle ; Roussel, Anne-Marie ; van den Berg, Henk ; Thurnham, David I.

In: British Journal of Nutrition, 2002, vol. 87, no. 1, p. 21-29