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Consortium of Swiss Academic Libraries

Impact of round-the-clock CSF Gram stain on empirical therapy for suspected central nervous system infections

Tissot, F. ; Prod'hom, G. ; Manuel, O. ; Greub, G.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 9, p. 1849-1857

Université de Fribourg

Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome

Pecze, Laszlo ; Randi, Elisa B. ; Szabo, Csaba

In: Molecular Medicine, 2020, vol. 26, no. 1, p. 102

Clinical observations and preclinical studies both suggest that Down syndrome (DS) may be associated with significant metabolic and bioenergetic alterations. However, the relevant scientific literature has not yet been systematically reviewed. The aim of the current study was to conduct a meta-analysis of metabolites involved in bioenergetics pathways in DS to conclusively determine the...

Université de Fribourg

Sex and age dependencies of aqueductal cerebrospinal fluid dynamics parameters in healthy subjects

Sartoretti, Thomas ; Wyss, Michael ; Sartoretti, Elisabeth ; Reischauer, Carolin ; Hainc, Nicolin ; Graf, Nicole ; Binkert, Christoph ; Najafi, Arash ; Sartoretti-Schefer, Sabine

In: Frontiers in Aging Neuroscience, 2019, vol. 11, p. 199

Objectives: To assess the influence of age and sex on 10 cerebrospinal fluid (CSF) flow dynamics parameters measured with an MR phase contrast (PC) sequence within the cerebral aqueduct at the level of the intercollicular sulcus.Materials and Methods: 128 healthy subjects (66 female subjects with a mean age of 52.9 years and 62 male subjects with a mean age of 51.8 years) with a normal Evans...