Université de Fribourg

Similarities and differences in altitudinal versus latitudinal variation for morphological traits in Drosophila melanogaster

Klepsatel, Peter ; Gáliková, Martina ; Huber, Christian D. ; Flatt, Thomas

In: Evolution, 2014, vol. 68, no. 5, p. 1385–1398

Understanding how natural environments shape phenotypic variation is a major aim in evolutionary biology. Here, we have examined clinal, likely genetically based variation in morphology among 19 populations of the fruit fly (Drosophila melanogaster) from Africa and Europe, spanning a range from sea level to 3000 m altitude and including locations approximating the southern and northern range...

Université de Fribourg

The case of GWAS of obesity: does body weight control play by the rules?

Müller, Manfred J. ; Geisler, Corinna ; Blundell, John ; Dulloo, Abdul G. ; Schutz, Yves ; Krawczak, Michael ; Bosy-Westphal, Anja ; Enderle, Janna ; Heymsfield, Steven B.

In: International Journal of Obesity, 2018, vol. 42, no. 8, p. 1395–1405

As yet, genome-wide association studies (GWAS) have not added much to our understanding of the mechanisms of body weight control and of the etiology of obesity. This shortcoming is widely attributed to the complexity of the issues. The appeal of this explanation notwithstanding, we surmise that (i) an oversimplification of the phenotype (namely by the use of crude anthropometric traits) and...

Consortium of Swiss Academic Libraries

Correlation and response relevance in sequence learning

Cock, Josephine ; Meier, Beat

In: Psychological Research, 2013, vol. 77, no. 4, p. 449-462