In: International journal of molecular sciences, 2021, vol. 22, no. 12, p. 24
Inflammation in the tumor microenvironment has been shown to promote disease progression in pancreatic ductal adenocarcinoma (PDAC); however, the role of macrophage metabolism in promoting inflammation is unclear. Using an orthotopic mouse model of PDAC, we demonstrate that macrophages from tumor-bearing mice exhibit elevated glycolysis. Macrophage- specific deletion of Glucose Transporter 1...
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In: Journal of International Dispute Settlement, 2018, vol. 9, no. 3, p. 339-344
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In: Digestive Diseases and Sciences, 2015, vol. 60, no. 10, p. 3053-3061
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In: Leukemia, 2021, p. 7 p
The prognostic significance of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was identified when the biology of the disease was poorly understood and therapy was not effective. We assessed the clinical and biological significance of LDT in 848 CLL patients in a real-life setting and the context of new biomarkers and effective therapy. A short LDT (≤12 months) was...
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In: Blood, 2020, vol. 135, no. 21, p. 1859–1869
Most patients with chronic lymphocytic leukemia (CLL) are diagnosed with early-stage disease and managed with active surveillance. The individual course of patients with early-stage CLL is heterogeneous, and their probability of needing treatment is hardly anticipated at diagnosis. We aimed at developing an international prognostic score to predict time to first treatment (TTFT) in patients...
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In: The breast, 2020, vol. 52, p. 110-115
Background: Corona Virus Disease 19 (COVID-19) had a worldwide negative impact on healthcare systems, which were not used to coping with such pandemic. Adaptation strategies prioritizing COVID-19 patients included triage of patients and reduction or re-allocation of other services. The aim of our survey was to provide a real time international snapshot of modifications of breast cancer...
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In: Cancers, 2020, vol. 12, no. 1, p. 223
Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...
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In: Archives of Gynecology and Obstetrics, 2014, vol. 289, no. 4, p. 903-909
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In: Virchows Archiv, 2014, vol. 464, no. 3, p. 359-365
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In: Breast Cancer Research and Treatment, 2014, vol. 143, no. 1, p. 159-169
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