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Increasing cancer risk over calendar year in people with multiple sclerosis : a case–control study

Zecca, Chiara ; Disanto, Giulio ; Sacco, Rosaria ; MacLachlan, Sharon ; Kuhle, Jens ; Ramagopalan, Sreeram V. ; Gobbi, Claudio

In: Journal of Neurology, 2021, no. 268, p. 817–824

Background: Data on cancer prevalence and incidence in multiple sclerosis (MS) patients are controversial. This study is aimed at estimating cancer risk in MS patients. Methods: Nested case–control study using data collected between 01/01/1987 and 28/02/2016 from the United Kingdom Clinical Practice Research Datalink. Cancer diagnoses after first MS code (index date) was counted in 10,204 MS...

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

Jürgens, Tanja ; Jafari, Mehrnoosh ; Kreutzfeldt, Mario ; Bahn, Erik ; Brück, Wolfgang ; Kerschensteiner, Martin ; Merkler, Doron

In: Brain, 2016, vol. 139, no. 1, p. 39-46

The Role of the Cerebellum in Multiple Sclerosis

Weier, Katrin ; Banwell, Brenda ; Cerasa, Antonio ; Collins, D. ; Dogonowski, Anne-Marie ; Lassmann, Hans ; Quattrone, Aldo ; Sahraian, Mohammad ; Siebner, Hartwig ; Sprenger, Till

In: The Cerebellum, 2015, vol. 14, no. 3, p. 364-374

Nerve ultrasound for differentiation between amyotrophic lateral sclerosis and multifocal motor neuropathy

Grimm, Alexander ; Décard, Bernhard ; Athanasopoulou, Ioanna ; Schweikert, Kathi ; Sinnreich, Michael ; Axer, Hubertus

In: Journal of Neurology, 2015, vol. 262, no. 4, p. 870-880

CSF lactate for accurate diagnosis of community-acquired bacterial meningitis

Giulieri, S. ; Chapuis-Taillard, C. ; Jaton, K. ; Cometta, A. ; Chuard, C. ; Hugli, O. ; Du Pasquier, R. ; Bille, J. ; Meylan, P. ; Manuel, O. ; Marchetti, O.

In: European Journal of Clinical Microbiology & Infectious Diseases, 2015, vol. 34, no. 10, p. 2049-2055

Magnetization transfer ratio in lesions rather than normal-appearing brain relates to disability in patients with multiple sclerosis

Amann, Michael ; Papadopoulou, Athina ; Andelova, Michaela ; Magon, Stefano ; Mueller-Lenke, Nicole ; Naegelin, Yvonne ; Stippich, Christoph ; Radue, Ernst ; Bieri, Oliver ; Kappos, Ludwig ; Sprenger, Till

In: Journal of Neurology, 2015, vol. 262, no. 8, p. 1909-1917

Progressive multifocal leukoencephalopathy in common variable immunodeficiency: mitigated course under mirtazapine and mefloquine

Kurmann, Rebekka ; Weisstanner, Christian ; Kardas, Piotr ; Hirsch, Hans ; Wiest, Roland ; Lämmle, Bernhard ; Furrer, Hansjakob ; Du Pasquier, Renaud ; Bassetti, Claudio ; Sturzenegger, Mathias ; Krestel, Heinz

In: Journal of NeuroVirology, 2015, vol. 21, no. 6, p. 694-701

CD4+ T-Cell Reactivity to Orexin/Hypocretin in Patients With Narcolepsy Type 1

Ramberger, Melanie ; Högl, Birgit ; Stefani, Ambra ; Mitterling, Thomas ; Reindl, Markus ; Lutterotti, Andreas

In: SLEEP, 2016, vol. 40, no. 3, p. -

Amide proton transfer weighted imaging shows differences in multiple sclerosis lesions and white matter hyperintensities of presumed vascular origin

Sartoretti, Elisabeth ; Sartoretti, Thomas ; Wyss, Michael ; Becker, Anton S. ; Schwenk, Árpád ; Smoorenburg, Luuk van ; Najafi, Arash ; Binkert, Christoph ; Thoeny, Harriet C. ; Zhou, Jinyuan ; Jiang, Shanshan ; Graf, Nicole ; Czell, David ; Sartoretti-Schefer, Sabine ; Reischauer, Carolin

In: Frontiers in Neurology, 2019, vol. 10, p. -

Objectives: To assess the ability of 3D amide proton transfer weighted (APTw) imaging based on magnetization transfer analysis to discriminate between multiple sclerosis lesions (MSL) and white matter hyperintensities of presumed vascular origin (WMH) and to compare APTw signal intensity of healthy white matter (healthy WM) with APTw signal intensity of MSL and WHM.Materials and Methods: A...

Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice

Volpi, Vera G. ; Ferri, Cinzia ; Fregno, Ilaria ; Del Carro, Ubaldo ; Bianchi, Francesca ; Scapin, Cristina ; Pettinato, Emanuela ; Solda, Tatiana ; Feltri, M. Laura ; Molinari, Maurizio ; Wrabetz, Lawrence ; D’Antonio, Maurizio

In: PLOS genetics, 2019, vol. 15, no. 4, p. e1008069

In the peripheral nervous system (PNS) myelinating Schwann cells synthesize large amounts of myelin protein zero (P0) glycoprotein, an abundant component of peripheral nerve myelin. In humans, mutations in P0 cause the demyelinating Charcot-Marie-Tooth 1B (CMT1B) neuropathy, one of the most diffused genetic disorders of the PNS. We previously showed that several mutations, such as the...