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6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice

Jeanbart, Laura ; Kourtis, Iraklis ; van der Vlies, André ; Swartz, Melody ; Hubbell, Jeffrey

In: Cancer Immunology, Immunotherapy, 2015, vol. 64, no. 8, p. 1033-1046

Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

Jang, Jae-Hwi ; Baerts, Lesley ; Waumans, Yannick ; De Meester, Ingrid ; Yamada, Yoshito ; Limani, Perparim ; Gil-Bazo, Ignacio ; Weder, Walter ; Jungraithmayr, Wolfgang

In: Clinical & Experimental Metastasis, 2015, vol. 32, no. 7, p. 677-687

In vitro activity of gentamicin as an adjunct to penicillin against biofilm group B Streptococcus

Ruppen, Corinne ; Hemphill, Andrew ; Sendi, Parham

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 2, p. 444-447

The inoculum effect of Escherichia coli expressing mcr-1 or not on colistin activity in a murine model of peritonitis

Fantin, B. ; Poujade, J. ; Grégoire, N. ; Chau, F. ; Roujansky, A. ; Kieffer, Nicolas ; Berleur, M. ; Couet, W. ; Nordmann, Patrice

In: Clinical Microbiology and Infection, 2019, vol. 25, no. 12, p. 1563.e5-1563.e8

Colistin often remains the last resort antibiotic active against carbapenemase- producing Enterobacteriaceae. However, while in vitro inoculum effect has been reported, therapeutic relevance of this phenomenon remains questioned.Methods: Ten E. coli strains were used that included the wild-type CFT073 and its transconjugant CFT073-MCR-1 and eight susceptible clinical isolates. Mice with ...

A Protective Allergy Vaccine Based on CpG- and Protamine-Containing PLGA Microparticles

Gómez, Julia ; Fischer, Stefan ; Csaba, Noèmi ; Kündig, Thomas ; Merkle, Hans ; Gander, Bruno ; Johansen, Pål

In: Pharmaceutical Research, 2007, vol. 24, no. 10, p. 1927-1935

Composition and Surface Charge of DNA-Loaded Microparticles Determine Maturation and Cytokine Secretion in Human Dendritic Cells

Jilek, Samantha ; Ulrich, Michael ; Merkle, Hans ; Walter, Elke

In: Pharmaceutical Research, 2004, vol. 21, no. 7, p. 1240-1247

In Vitro Inhibition of Coagulase-Negative Staphylococci by Vancomycin/Aminoglycoside-Loaded Cement Spacers

Streuli, J. ; Exner, G. ; Reize, C. ; Merkofer, C. ; Scott, C. ; Zbinden, R.

In: Infection, 2006, vol. 34, no. 2, p. 81-86

Alpine ibex ( Capra i : ibex ) is not a reservoir for chlamydial infections of domestic ruminants and humans

Holzwarth, Nathalie ; Pospischil, Andreas ; Marreros, Nelson ; Ryser-Degiorgis, Marie-Pierre ; Mavrot, Fabien ; Frey, Joachim ; Thoma, Rudolf ; Borel, Nicole

In: European Journal of Wildlife Research, 2011, vol. 57, no. 2, p. 233-240

On Technological and Immunological Benefits of Multivalent Single-Injection Microsphere Vaccines

Boehm, Gérard ; Peyre, Marisa ; Sesardic, Dorothea ; Huskisson, Rachel ; Mawas, Fatme ; Douglas, Alexandra ; Xing, Dorothy ; Merkle, Hans ; Gander, Bruno ; Johansen, Pål

In: Pharmaceutical Research, 2002, vol. 19, no. 9, p. 1330-1336

Ligand-Specific Targeting of Microspheres to Phagocytes by Surface Modification with Poly(L-Lysine)-Grafted Poly(Ethylene Glycol) Conjugate

Faraasen, Sofia ; Vörös, János ; Csúcs, Gábor ; Textor, Marcus ; Merkle, Hans ; Walter, Elke

In: Pharmaceutical Research, 2003, vol. 20, no. 2, p. 237-246