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Therapeutic efficacy of antibodies lacking FcγR against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies

Williams, Katherine L. ; Sukupolvi-Petty, Soila ; Beltramello, Martina ; Johnson, Syd ; Sallusto, Federica ; Lanzavecchia, Antonio ; Diamond, Michael S. ; Harris, Eva

In: Plos pathogens, 2013, vol. 9, no. 2, p. e1003157

Dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) are life-threatening complications following infection with one of the four serotypes of dengue virus (DENV). At present, no vaccine or antiviral therapies are available against dengue. Here, we characterized a panel of eight human or mouse-human chimeric monoclonal antibodies (MAbs) and their modified variants lacking effector...

Author's response to "Letter to the editor: unvalidated antibodies and misleading results”

Muenst, S. ; Tzankov, A. ; Gillanders, W. ; Soysal, S.

In: Breast Cancer Research and Treatment, 2014, vol. 147, no. 2, p. 459-462

MET Y1253D-activating point mutation and development of distant metastasis in advanced head and neck cancers

Ghadjar, Pirus ; Blank-Liss, Wieslawa ; Simcock, Mathew ; Hegyi, Ivan ; Beer, Karl ; Moch, Holger ; Aebersold, Daniel ; Zimmer, Yitzhak

In: Clinical & Experimental Metastasis, 2009, vol. 26, no. 7, p. 809-815

Molecular markers in gliomas: impact for the clinician

Hofer, Silvia ; Lassman, Andrew

In: Targeted Oncology, 2010, vol. 5, no. 3, p. 201-210

Expression and amplification of therapeutic target genes in retinoblastoma

Bösch, Doris ; Pache, Mona ; Simon, Ronald ; Schraml, Peter ; Glatz, Katharina ; Mirlacher, Martina ; Flammer, Josef ; Sauter, Guido ; Meyer, Peter

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2005, vol. 243, no. 2, p. 156-162

PI3Kinase signaling in glioblastoma

Lino, M. ; Merlo, A.

In: Journal of Neuro-Oncology, 2011, vol. 103, no. 3, p. 417-427

In vitro characterization of 177Lu-radiolabelled chimeric anti-CD20 monoclonal antibody and a preliminary dosimetry study

Forrer, Flavio ; Chen, Jianhua ; Fani, Melpomeni ; Powell, Pia ; Lohri, Andreas ; Müller-Brand, Jan ; Moldenhauer, Gerhard ; Maecke, Helmut

In: European Journal of Nuclear Medicine and Molecular Imaging, 2009, vol. 36, no. 9, p. 1443-1452

KIT , PDGFRα and EGFR analysis in nephroblastoma

Wetli, Sylvia ; Leuschner, Ivo ; Harms, Dieter ; Rufle, Alex ; Foerster, Anja ; Bihl, Michel ; Graf, Norbert ; Furtwaengler, Roikos ; Paulussen, Michael ; Briner, Jakob ; Aslanidis, Charalampos ; Schmitz, Gerd ; Tornillo, Luigi ; Mihatsch, Michael ; Zlobec, Inti ; Bruder, Elisabeth

In: Virchows Archiv, 2008, vol. 452, no. 6, p. 637-650

NY-BR-1 protein expression in breast carcinoma: a mammary gland differentiation antigen as target for cancer immunotherapy

Theurillat, Jean-Philippe ; Zürrer-Härdi, Ursina ; Varga, Zsuzsanna ; Storz, Martina ; Probst-Hensch, Nicole ; Seifert, Burkhardt ; Fehr, Mathias ; Fink, Daniel ; Ferrone, Soldano ; Pestalozzi, Bernhard ; Jungbluth, Achim ; Chen, Yao-Tseng ; Jäger, Dirk ; Knuth, Alexander ; Moch, Holger

In: Cancer Immunology, Immunotherapy, 2007, vol. 56, no. 11, p. 1723-1731

Comparative study of recent wide-pore materials of different stationary phase morphology, applied for the reversed-phase analysis of recombinant monoclonal antibodies

Fekete, Szabolcs ; Veuthey, Jean-Luc ; Eeltink, Sebastiaan ; Guillarme, Davy

In: Analytical and Bioanalytical Chemistry, 2013, vol. 405, no. 10, p. 3137-3151