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Mobile phones as medical devices in mental disorder treatment: an overview

Gravenhorst, Franz ; Muaremi, Amir ; Bardram, Jakob ; Grünerbl, Agnes ; Mayora, Oscar ; Wurzer, Gabriel ; Frost, Mads ; Osmani, Venet ; Arnrich, Bert ; Lukowicz, Paul ; Tröster, Gerhard

In: Personal and Ubiquitous Computing, 2015, vol. 19, no. 2, p. 335-353

Data mining-based statistical analysis of biological data uncovers hidden significance: clustering Hashimoto's thyroiditis patients based on the response of their PBMC with IL-2 and IFN-γ secretion to stimulation with Hsp60

Tonello, Lucio ; Conway de Macario, Everly ; Marino Gammazza, Antonella ; Cocchi, Massimo ; Gabrielli, Fabio ; Zummo, Giovanni ; Cappello, Francesco ; Macario, Alberto

In: Cell Stress and Chaperones, 2015, vol. 20, no. 2, p. 391-395

Measuring localized viscoelasticity of the vitreous body using intraocular microprobes

Pokki, Juho ; Ergeneman, Olgaç ; Sevim, Semih ; Enzmann, Volker ; Torun, Hamdi ; Nelson, Bradley

In: Biomedical Microdevices, 2015, vol. 17, no. 5, p. 1-9

The role of the acquired immune response in systemic sclerosis

Chizzolini, Carlo ; Boin, Francesco

In: Seminars in Immunopathology, 2015, vol. 37, no. 5, p. 519-528

The 2013 European Seismic Hazard Model: key components and results

Woessner, Jochen ; Laurentiu, Danciu ; Giardini, Domenico ; Crowley, Helen ; Cotton, Fabrice ; Grünthal, Gottfried ; Valensise, Gianluca ; Arvidsson, Ronald ; Basili, Roberto ; Demircioglu, Mine ; Hiemer, Stefan ; Meletti, Carlo ; Musson, Roger ; Rovida, Andrea ; Sesetyan, Karin ; Stucchi, Massimiliano

In: Bulletin of Earthquake Engineering, 2015, vol. 13, no. 12, p. 3553-3596

Sterile-filtered saliva is a strong inducer of IL-6 and IL-8 in oral fibroblasts

Cvikl, Barbara ; Lussi, Adrian ; Moritz, Andreas ; Sculean, Anton ; Gruber, Reinhard

In: Clinical Oral Investigations, 2015, vol. 19, no. 2, p. 385-399

Clinical onset and course, response to treatment and outcome in 24 patients with the cblE or cblG remethylation defect complemented by genetic and in vitro enzyme study data

Huemer, M. ; Bürer, C. ; Ješina, P. ; Kožich, V. ; Landolt, M. ; Suormala, T. ; Fowler, B. ; Augoustides- Savvopoulou, P. ; Blair, E. ; Brennerova, K. ; Broomfield, A. ; De Meirleir, L. ; Gökcay, G. ; Hennermann, J. ; Jardine, P. ; Koch, J. ; Lorenzl, S. ; Lotz-Havla, A. ; Noss, J. ; Parini, R. ; Peters, H. ; Plecko, B. ; Ramos, F. ; Schlune, A. ; Tsiakas, K. ; Zerjav Tansek, M. ; Baumgartner, M.

In: Journal of Inherited Metabolic Disease, 2015, vol. 38, no. 5, p. 957-967

The FKBP4 gene, encoding a regulator of the androgen receptor signaling pathway, is a novel candidate gene for androgen insensitivity syndrome

Ilaslan, Erkut ; Markosyan, Renata ; Sproll, Patrick ; Stevenson, Brian J. ; Sajek, Malgorzata ; Sajek, Marcin P. ; Hayrapetyan, Hasmik ; Sarkisian, Tamara ; Livshits, Ludmila ; Nef, Serge ; Jaruzelska, Jadwiga ; Kusz-Zamelczyk, Kamila

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 21, p. 8403

Androgen insensitivity syndrome (AIS), manifesting incomplete virilization in 46,XY individuals, is caused mostly by androgen receptor (AR) gene mutations. Therefore, a search for AR mutations is a routine approach in AIS diagnosis. However, some AIS patients lack AR mutations, which complicates the diagnosis. Here, we describe a patient suffering from partial androgen insensitivity syndrome...

An inflamed human alveolar model for testing the efficiency of anti-inflammatory drugs in vitro

Drasler, Barbara ; Karakocak, Bedia Begum ; Tankus, Esma Bahar ; Barosova, Hana ; Abe, Jun ; Sousa de Almeida, Mauro ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Frontiers in Bioengineering and Biotechnology, 2020, vol. 8, p. -

A large number of prevalent lung diseases is associated with tissue inflammation. Clinically, corticosteroid therapies are applied systemically or via inhalation for the treatment of lung inflammation, and a number of novel therapies are being developed that require preclinical testing. In alveoli, macrophages and dendritic cells play a key role in initiating and diminishing pro-inflammatory...

Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis

Hu, Dan ; Notarbartolo, Samuele ; Croonenborghs, Tom ; Patel, Bonny ; Cialic, Ron ; Yang, Tun-Hsiang ; Aschenbrenner, Dominik ; Andersson, Karin M. ; Gattorno, Marco ; Pham, Minh ; Kivisakk, Pia ; Pierre, Isabelle V. ; Lee, Youjin ; Kiani, Karun ; Bokarewa, Maria ; Tjon, Emily ; Pochet, Nathalie ; Sallusto, Federica ; Kuchroo, Vijay K. ; Weiner, Howard L.

In: Nature communications, 2017, vol. 8, p. 1600

We have previously reported the molecular signature of murine pathogenic TH17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals. Here we show that human peripheral blood IFN-γ+IL-17+ (TH1/17) and IFN-γ−IL-17+ (TH17) CD4+ T cells display distinct transcriptional profiles in high-throughput transcription analyses. Compared to TH17 cells, TH1/17 cells have gene...