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Université de Fribourg

VAPYRIN-like is required for development of the moss Physcomitrella patens

Rathgeb, Ursina ; Chen, Min ; Buron, Flavien ; Feddermann, Nadja ; Schorderet, Martine ; Raisin, Axelle ; Häberli, Gabrielle-Yasymi ; Marc-Martin, Sophie ; Keller, Jean ; Delaux, Pierre-Marc ; Schaefer, Didier G. ; Reinhardt, Didier

In: Development, 2020, vol. 147, no. 11, p. dev184762

The VAPYRIN (VPY) gene in Medicago truncatula and Petunia hybrida is required for arbuscular mycorrhizal (AM) symbiosis. The moss Physcomitrella patens has a close homolog (VPY-like, VPYL), although it does not form AM. Here, we explore the phylogeny of VPY and VPYL in land plants, and study the expression and developmental function of VPYL in P. patens. We show that VPYL is expressed ...

Université de Fribourg

LCO receptors involved in arbuscular mycorrhiza are functional for rhizobia perception in legumes

Girardin, Ariane ; Wang, Tongming ; Ding, Yi ; Keller, Jean ; Buendia, Luis ; Gaston, Mégane ; Ribeyre, Camille ; Gasciolli, Virginie ; Auriac, Marie-Christine ; Vernié, Tatiana ; Bendahmane, Abdelhafid ; Ried, Martina Katharina ; Parniske, Martin ; Morel, Patrice ; Vandenbussche, Michiel ; Schorderet, Martine ; Reinhardt, Didier ; Delaux, Pierre-Marc ; Bono, Jean-Jacques ; Lefebvre, Benoit

In: Current Biology, 2019, vol. 29, no. 24, p. 4249-4259.e5

Bacterial lipo-chitooligosaccharides (LCOs) are key mediators of the nitrogen-fixing root nodule symbiosis (RNS) in legumes. The isolation of LCOs from arbuscular mycorrhizal fungi suggested that LCOs are also signaling molecules in arbuscular mycorrhiza (AM). However, the corresponding plant receptors have remained uncharacterized. Here we show that petunia and tomato mutants in the LysM ...

Università della Svizzera italiana

P2X7 receptor restrains pathogenic Tfh cell generation in systemic lupus erythematosus

Faliti, Caterina E. ; Gualtierotti, Roberta ; Rottoli, Elsa ; Gerosa, Maria ; Perruzza, Lisa ; Romagnani, Andrea ; Pellegrini, Giovanni ; De Ponte Conti, Benedetta ; Rossi, Riccardo L. ; Idzko, Marco ; Mazza, Emilia M.C. ; Bicciato, Silvio ; Traggiai, Elisabetta ; Meroni, Pier Luigi ; Grassi, Fabio

In: Journal of Experimental Medicine, 2019, vol. 216, no. 2, p. 317-336

Altered control of T follicular helper (Tfh) cells can lead to generation of autoantibodies and autoimmune manifestations. Signaling pathways that selectively limit pathogenic responses without affecting the protective function of Tfh cells are unknown. Here we show that the ATP-gated ionotropic P2X7 receptor restricts the expansion of aberrant Tfh cells and the generation of self-reactive...

Université de Fribourg

Checklist of gypsophilous vascular flora in Italy

Musarella, Carmelo Maria ; Mendoza-Fernández, Antonio Jesús ; Mota, Juan Francisco ; Alessandrini, Alessandro ; Bacchetta, Gianluigi ; Brullo, Salvatore ; Caldarella, Orazio ; Ciaschetti, Giampiero ; Conti, Fabio ; Martino, Luciano Di ; Falci, Amedeo ; Gianguzzi, Lorenzo ; Guarino, Riccardo ; Manzi, Aurelio ; Minissale, Pietro ; Montanari, Sergio ; Pasta, Salvatore ; Peruzzi, Lorenzo ; Podda, Lina ; Sciandrello, Saverio ; Scuderi, Leonardo ; Troia, Angelo ; Spampinato, Giovanni

In: PhytoKeys, 2018, vol. 103, p. 61–82

Our understanding of the richness and uniqueness of the flora growing on gypsum substrates in Italy has grown significantly since the 19th century and, even today, new plant species are still being discovered. However, the plants and plant communities, growing on gypsum substrates in Italy, are still a relatively unknown subject. The main aim of this paper was to elaborate a checklist of the...