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Università della Svizzera italiana

Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns

Juanola, Oriol ; Hassan, Mohsin ; Kumar, Pavitra ; Yilmaz, Bahtiyar ; Keller, Irene ; Simillion, Cédric ; Engelmann, Cornelius ; Tacke, Frank ; Dufour, Jean-François ; De Gottardi, Andrea ; Moghadamrad, Sheida

In: Gut microbes, 2021, vol. 13, no. 1, p. 20

Intestinal microbiota regulates multiple host metabolic and immunological processes. Consequently, any difference in its qualitative and quantitative composition is susceptible to exert significant effects, in particular along the gut-liver axis. Indeed, recent findings suggest that such changes modulate the severity and the evolution of a wide spectrum of hepatobiliary disorders. However, the...

Università della Svizzera italiana

Dietary chloride deficiency syndrome : pathophysiology, history, and systematic literature review

Signorelli, Giulia C. ; Bianchetti, Mario G. ; Jermini, Luca M. M. ; Agostoni, Carlo ; Milani, Gregorio P. ; Simonetti, Giacomo D. ; Lava, Sebastiano A. G.

In: Nutrients, 2020, vol. 12, no. 11, p. 10 p

Metabolic alkalosis may develop as a consequence of urinary chloride (and sodium) wasting, excessive loss of salt in the sweat, or intestinal chloride wasting, among other causes. There is also a likely underrecognized association between poor salt intake and the mentioned electrolyte and acid–base abnormality. In patients with excessive loss of salt in the sweat or poor salt intake, the...

Consortium of Swiss Academic Libraries

The intestinal microbiota: its role in health and disease

Biedermann, Luc ; Rogler, Gerhard

In: European Journal of Pediatrics, 2015, vol. 174, no. 2, p. 151-167