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Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaques

Meletta, Romana ; Borel, Nicole ; Stolzmann, Paul ; Astolfo, Alberto ; Klohs, Jan ; Stampanoni, Marco ; Rudin, Markus ; Schibli, Roger ; Krämer, Stefanie ; Müller Herde, Adrienne

In: The International Journal of Cardiovascular Imaging, 2015, vol. 31, no. 7, p. 1425-1434

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, Manuel R. ; Gencer, Baris ; Adam, Luise ; Feller, Martin ; Collet, Tinh-Hai ; da Costa, Bruno R. ; Moutzouri, Elisavet ; Dopheide, Jörn ; Depairon, Michèle ; Sykiotis, Gerasimos P. ; Kearney, Patricia ; Gussekloo, Jacobijn ; Westendorp, Rudi ; Stott, David J. ; Bauer, Douglas C. ; Rodondi, Nicolas

In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 8, p. 2988-2997

Poly(ADP-ribose) polymerase inhibition in acute lung injury. A reemerging concept

Szabo, Csaba ; Martins, Vanessa ; Liaudet, Lucas

In: American Journal of Respiratory Cell and Molecular Biology, 2020, vol. 63, no. 5, p. 571–590

PARP1, the major isoform of a family of ADP-ribosylating enzymes, has been implicated in the regulation of various biological processes including DNA repair, gene transcription, and cell death. The concept that PARP1 becomes activated in acute lung injury (ALI) and that pharmacological inhibition or genetic deletion of this enzyme can provide therapeutic benefits emerged over 20 years ago....

Hypoxia enhances endothelial intercellular adhesion molecule 1 protein level through upregulation of arginase type II and mitochondrial oxidative stress

Liang, Xiujie ; Arullampalam, Prakash ; Yang, Zhihong ; Ming, Xiu-Fen

In: Frontiers in Physiology, 2019, vol. 10, p. -

Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance the expression of endothelial inflammatory adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). In this study, we investigate the role of Arg-II in...

Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development

Winnik, Stephan ; Gaul, Daniel ; Preitner, Frédéric ; Lohmann, Christine ; Weber, Julien ; Miranda, Melroy ; Liu, Yilei ; van Tits, Lambertus ; Mateos, José ; Brokopp, Chad ; Auwerx, Johan ; Thorens, Bernard ; Lüscher, Thomas ; Matter, Christian

In: Basic Research in Cardiology, 2014, vol. 109, no. 1, p. 1-15

Interaction between widening of diameter of abdominal aorta and cardiovascular risk factors and atherosclerosis burden

Glauser, Frédéric ; Mazzolai, Lucia ; Darioli, Roger ; Depairon, Michèle

In: Internal and Emergency Medicine, 2014, vol. 9, no. 4, p. 411-417

Immunological aspects of atherosclerosis

Garrido-Urbani, S. ; Meguenani, M. ; Montecucco, F. ; Imhof, B.

In: Seminars in Immunopathology, 2014, vol. 36, no. 1, p. 73-91

Tight junction dynamics: the role of junctional adhesion molecules (JAMs)

Garrido-Urbani, S. ; Bradfield, P. ; Imhof, B.

In: Cell and Tissue Research, 2014, vol. 355, no. 3, p. 701-715

Human endothelial dysfunction: EDRFs

Flammer, Andreas ; Lüscher, Thomas

In: Pflügers Archiv - European Journal of Physiology, 2010, vol. 459, no. 6, p. 1005-1013

The emerging role of the endocannabinoid system in cardiovascular disease

Pacher, Pál ; Steffens, Sabine

In: Seminars in Immunopathology, 2009, vol. 31, no. 1, p. 63-77