Università della Svizzera italiana

Richter syndrome

Condoluci, Adalgisa ; Rossi, Davide

In: Current Oncology Reports, 2021, vol. 23, no. 3, p. 10

Purpose of Review Richter syndrome (RS) is an uncommon but aggressive evolution of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). RS is an unmet clinical need in the field of CLL. Recent advances in understanding the biology of this condition provide the rationale for testing new therapeutic concepts in order to improve the outcome of patients developing RS, which is so far...

Università della Svizzera italiana

Electrolyte and acid-base disorders triggered by aminoglycoside or colistin therapy : a systematic review

Scoglio, Martin ; Bronz, Gabriel ; Rinoldi, Pietro O. ; Faré, Pietro B. ; Betti, Céline ; Bianchetti, Mario G. ; Simonetti, Giacomo D. ; Gennaro, Viola ; Renzi, Samuele ; Lava, Sebastiano A. G. ; Milani, Gregorio P.

In: Antibiotics, 2021, vol. 10, no. 2, p. 9

Aminoglycoside or colistin therapy may alter the renal tubular function without decreasing the glomerular filtration rate. This association has never been extensively investigated. We conducted a systematic review of the literature following the Preferred Reporting Items for Systematic Reviews and Meta- Analyses recommendations. Databases searched included United States National Library of...

Consortium of Swiss Academic Libraries

Sarcoma of the heart: survival after surgery

Niclauss, Lars ; Montemurro, Michael ; Kirsch, Matthias ; Prêtre, René

In: Interactive CardioVascular and Thoracic Surgery, 2018, vol. 27, no. 2, p. 198-201

Università della Svizzera italiana

Lymphocyte doubling time in chronic lymphocytic leukemia modern era : a real-life study in 848 unselected patients

Baumann, Tycho ; Moia, Riccardo ; Gaidano, Gianluca ; Delgado, Julio ; Condoluci, Adalgisa ; Villamor, Neus ; Payedimarri, Anil Babu ; Costa, Dolors ; Patriarca, Andrea ; Jiménez-Vicente, Carlos ; Rossi, Davide ; Montserrat, Emili

In: Leukemia, 2021, p. 7 p

The prognostic significance of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was identified when the biology of the disease was poorly understood and therapy was not effective. We assessed the clinical and biological significance of LDT in 848 CLL patients in a real-life setting and the context of new biomarkers and effective therapy. A short LDT (≤12 months) was...