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Synaptic Adhesion Molecules Regulate the Integration of New Granule Neurons in the Postnatal Mouse Hippocampus and their Impact on Spatial Memory

Krzisch, Marine ; Fülling, Christine ; Jabinet, Laura ; Armida, Jan ; Gebara, Elias ; Cassé, Frédéric ; Habbas, Samia ; Volterra, Andrea ; Hornung, Jean-Pierre ; Toni, Nicolas

In: Cerebral Cortex, 2017, vol. 27, no. 8, p. 4048-4059

Involvement of long non-coding RNAs in beta cell failure at the onset of type 1 diabetes in NOD mice

Motterle, Anna ; Gattesco, Sonia ; Caille, Dorothée ; Meda, Paolo ; Regazzi, Romano

In: Diabetologia, 2015, vol. 58, no. 8, p. 1827-1835

Nerve ultrasound for differentiation between amyotrophic lateral sclerosis and multifocal motor neuropathy

Grimm, Alexander ; Décard, Bernhard ; Athanasopoulou, Ioanna ; Schweikert, Kathi ; Sinnreich, Michael ; Axer, Hubertus

In: Journal of Neurology, 2015, vol. 262, no. 4, p. 870-880

Multimodal MRI Imaging of Apoptosis-Triggered Microstructural Alterations in the Postnatal Cerebral Cortex

Petrenko, Volodymyr ; van de Looij, Yohan ; Mihhailova, Jevgenia ; Salmon, Patrick ; Hüppi, Petra S. ; Sizonenko, Stéphane V. ; Kiss, Jozsef Z.

In: Cerebral Cortex, 2018, vol. 28, no. 3, p. 949-962

Schwann cells ER-associated degradation contributes to myelin maintenance in adult nerves and limits demyelination in CMT1B mice

Volpi, Vera G. ; Ferri, Cinzia ; Fregno, Ilaria ; Del Carro, Ubaldo ; Bianchi, Francesca ; Scapin, Cristina ; Pettinato, Emanuela ; Solda, Tatiana ; Feltri, M. Laura ; Molinari, Maurizio ; Wrabetz, Lawrence ; D’Antonio, Maurizio

In: PLOS genetics, 2019, vol. 15, no. 4, p. e1008069

In the peripheral nervous system (PNS) myelinating Schwann cells synthesize large amounts of myelin protein zero (P0) glycoprotein, an abundant component of peripheral nerve myelin. In humans, mutations in P0 cause the demyelinating Charcot-Marie-Tooth 1B (CMT1B) neuropathy, one of the most diffused genetic disorders of the PNS. We previously showed that several mutations, such as the...

Injured axons instruct schwann cells to build constricting actin spheres to accelerate axonal disintegration

Vaquié, Adrien ; Sauvain, Alizée ; Duman, Mert ; Nocera, Gianluigi ; Egger, Boris ; Meyenhofer, Felix ; Falquet, Laurent ; Bartesaghi, Luca ; Chrast, Roman ; Lamy, Christophe Maurice ; Bang, Seokyoung ; Lee, Seung-Ryeol ; Jeon, Noo Li ; Ruff, Sophie ; Jacob, Claire

In: Cell Reports, 2019, vol. 27, no. 11, p. 3152-3166.e7

After a peripheral nerve lesion, distal ends of injured axons disintegrate into small fragments that are subsequently cleared by Schwann cells and later by macrophages. Axonal debris clearing is an early step of the repair process that facilitates regeneration. We show here that Schwann cells promote distal cut axon disintegration for timely clearing. By combining cell-based and in vivo...

Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts

Schwalm, Stephanie ; Timcheva, Tankica Maneva ; Filipenko, Iuliia ; Ebadi, Mahsa ; Hofmann, Lotte P. ; Zangemeister-Wittke, Uwe ; Pfeilschifter, Josef ; Huwiler, Andrea

In: Biological Chemistry, 2015, vol. 396, no. 6-7, p. 813-825

Phosphoinositides and Charcot-Marie-Tooth disease: New keys to old questions

Suter, U.

In: Cellular and Molecular Life Sciences, 2007, vol. 64, no. 24, p. 3261-3265

Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings

Lövblad, Karl-Olof ; Ramelli, Gianpaolo ; Remonda, Luca ; Nirkko, Arto ; Ozdoba, Christoph ; Schroth, Gerhard

In: Pediatric Radiology, 1997, vol. 27, no. 2, p. 155-158

How Histone Deacetylases Control Myelination

Jacob, Claire ; Lebrun-Julien, Frédéric ; Suter, Ueli

In: Molecular Neurobiology, 2011, vol. 44, no. 3, p. 303-312