In: SLEEP, 2018, vol. 41, no. 7, p. -
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In: Oncotarget, 2015, vol. 6, no. 32, p. 33823-33833
The T cell immunoglobulin and mucin domain 3 (Tim-3) is a plasma membrane-associated receptor which is involved in a variety of biological responses in human immune cells. It is highly expressed in most acute myeloid leukaemia (AML) cells and therefore may serve as a possible target for AML therapy. However, its biochemical activities in primary human AML cells remain unclear. We therefore...
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In: Proceedings of the national academy of sciences of the United States of America, 2018, vol. 115, no. 40, p. 10112-10117
Viruses with membranes fuse them with cellular membranes, to transfer their genomes into cells at the beginning of infection. For Influenza virus, the membrane glycoprotein involved in fusion is the hemagglutinin (HA), the 3D structure of which is known from X-ray crystallographic studies. The soluble ectodomain fragments used in these studies lacked the “membrane anchor” portion of the...
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In: Computers and Electronics in Agriculture, 2019, vol. 157, p. 232–238
Maps of cropping practice, including the level of weed infestation, are useful planning tools e.g. for the assessment of the environmental impact of the crops, and Northern Italy is an important example due to the large and diverse agricultural production and the high weed infestation. Sentinel-2A is a new satellite with a high spatial and temporal resolution which potentially allows the...
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In: Journal of Nuclear Cardiology, 2010, vol. 17, no. 1, p. 4-7
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In: Archives of Gynecology and Obstetrics, 2012, vol. 285, no. 1, p. 21-25
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In: Pediatric Nephrology, 2004, vol. 19, no. 2, p. 229-231
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In: Annals of Hematology, 2009, vol. 88, no. 7, p. 681-685
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In: BioEssays, 2017/39/10/n/a-n/a
The evolutionary origin of synapses and neurons is an enigmatic subject that inspires much debate. Non-bilaterian metazoans, both with and without neurons and their closest relatives already contain many components of the molecular toolkits for synapse functions. The origin of these components and their assembly into ancient synaptic signaling machineries are particularly important in light...
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In: ACS Applied Materials & Interfaces, 2017, vol. 9, no. 35, p. 29571–29579
The magnetic separation of pathogenic compounds from body fluids is an appealing therapeutic concept. Recently, removal of a diverse array of pathogens has been demonstrated using extracorporeal dialysis-type devices. The contact time between the fluid and the magnetic beads in such devices is limited to a few minutes. This poses challenges, particularly if large compounds such as bacteria or...
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