In: Bioinformatics, 2017, vol. 33, no. 17, p. 2753-2755
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In: RSC Advances, 2020, vol. 10, no. 14, p. 8291–8302
Over the past decade, the rapid increase in the incidence of antibiotic-resistant bacteria has promoted research towards alternative therapeutics such as antimicrobial peptides (AMPs), but their biodegradability limits their application. Encapsulation into nanocarriers based on the self-assembly of surfactant-like lipids is emerging as a promising strategy for the improvement of AMPs'...
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In: RSC Advances, 2019, vol. 10, no. 1, p. 376–386
The design of functionalized polymer surfaces using bioactive compounds has grown rapidly over the past decade within many industries including biomedical, textile, microelectronics, bioprocessing and food packaging sectors. Polymer surfaces such as polystyrene (PS) must be treated using surface activation processes prior to the attachment of bioactive compounds. In this study, a new peptide...
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In: Nature Communications, 2019, vol. 10, no. 1, p. 1–12
Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) is involved in both intracellular membraneless organelles and extracellular tissues. Despite growing understanding of LLPS, molecular-level mechanisms behind this process are still not fully established. Here, we use histidine-rich squid beak proteins (HBPs) as model IDPs to shed light on molecular interactions...
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In: Advanced Functional Materials, 2019, p. 1904007
The rational design of alternative antimicrobial materials with reduced toxicity toward mammalian cells is highly desired due to the growing occurrence of bacteria resistant to conventional antibiotics. A promising approach is the design of lipid‐based antimicrobial nanocarriers. However, most of the commonly used polymer‐stabilized nanocarriers are cytotoxic. Herein, the design of a...
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In: Current Opinion in Colloid & Interface Science, 2019, vol. 39, p. 190–201
The daily diet is important for our survival, health, and wellbeing. Functional food materials, which tailor the digestion process, can help maintaining and even improving human health and lifestyle. Knowledge on how food products, particularly food emulsions such as milk, interact with the digestive system, where they transform into supramolecular structures, can have a direct impact on the...
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In: European Biophysics Journal, 2014, vol. 43, no. 2-3, p. 113-119
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In: Cellulose, 2014, vol. 21, no. 1, p. 367-382
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In: Acta Neuropathologica, 2019, vol. 137, no. 2, p. 239–257
Brain accumulation and aggregation of amyloid-β (Aβ) peptides is a critical step in the pathogenesis of Alzheimer’s disease (AD). Full-length Aβ peptides (mainly Aβ1–40 and Aβ1–42) are produced through sequential proteolytic cleavage of the amyloid precursor protein (APP) by β- and γ-secretases. However, studies of autopsy brain samples from AD patients have demonstrated that a...
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In: Frontiers in Psychology, 2018, vol. 9, no. 264, p. 1-12
Background: Despite on-going efforts to better understand dysregulated eating, the olfactory-gustatory deficits and food preferences in eating disorders (ED), and the mechanisms underlying the perception of and responses to food properties in anorexia nervosa (AN) and bulimia nervosa (BN) remain largely unknown; both during the course of the illness and compared to healthy populations. It is,...
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