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Molecular analysis of methicillin-resistant Staphylococcus pseudintermedius of feline origin from different European countries and North America

Kadlec, Kristina ; Schwarz, Stefan ; Perreten, Vincent ; Grönlund Andersson, Ulrika ; Finn, Maria ; Greko, Christina ; Moodley, Arshnee ; Kania, Stephen A. ; Frank, Linda A. ; Bemis, David A. ; Franco, Alessia ; Iurescia, Manuela ; Battisti, Antonio ; Duim, Birgitta ; Wagenaar, Jaap A. ; van Duijkeren, Engeline ; Weese, J. Scott ; Fitzgerald, J. Ross ; Rossano, Alexandra ; Guardabassi, Luca

In: Journal of Antimicrobial Chemotherapy, 2010, vol. 65, no. 8, p. 1826-1828

Clonal spread of methicillin-resistant Staphylococcus pseudintermedius in Europe and North America: an international multicentre study

Perreten, Vincent ; Kadlec, Kristina ; Schwarz, Stefan ; Grönlund Andersson, Ulrika ; Finn, Maria ; Greko, Christina ; Moodley, Arshnee ; Kania, Stephen A. ; Frank, Linda A. ; Bemis, David A. ; Franco, Alessia ; Iurescia, Manuela ; Battisti, Antonio ; Duim, Birgitta ; Wagenaar, Jaap A. ; van Duijkeren, Engeline ; Weese, J. Scott ; Fitzgerald, J. Ross ; Rossano, Alexandra ; Guardabassi, Luca

In: Journal of Antimicrobial Chemotherapy, 2010, vol. 65, no. 6, p. 1145-1154

The soil microbiota harbors a diversity of carbapenem-hydrolyzing β-lactamases of potential clinical relevance

Gudeta, Dereje Dadi ; Bortolaia, Valeria ; Amos, Greg ; Wellington, Elizabeth M. H. ; Brandt, Kristian K. ; Poirel, Laurent ; Nielsen, Jesper Boye ; Westh, Henrik ; Guardabassi, Luca

In: Antimicrobial Agents and Chemotherapy, 2016, vol. 60, no. 1, p. 151–160

The origin of carbapenem-hydrolyzing metallo-β-lactamases (MBLs) acquired by clinical bacteria is largely unknown. We investigated the frequency, host range, diversity, and functionality of MBLs in the soil microbiota. Twenty-five soil samples of different types and geographical origins were analyzed by antimicrobial selective culture, followed by phenotypic testing and expression of...

Chromobacterium spp. harbour Ambler class A β-lactamases showing high identity with KPC

Gudeta, Dereje Dadi ; Bortolaia, Valeria ; Jayol, Aurélie ; Poirel, Laurent ; Nordmann, Patrice ; Guardabassi, Luca

In: Journal of Antimicrobial Chemotherapy, 2016, p. -

Objectives The origin of KPC is unknown. The aim of this study was to detect progenitors of KPC in silico and to functionally verify their β-lactam hydrolysis activity.Methods The sequence of KPC-2 was used to mine the NCBI protein sequence database. The best non-KPC hits were analysed by amino acid (aa) alignment and phylogenetic tree construction....