Université de Fribourg

Pfm-like enzymes are a novel family of subclass b2 metallo-β-lactamases from Pseudomonas synxantha belonging to the Pseudomonas fluorescens complex

Poirel, Laurent ; Palmieri, Mattia ; Brilhante, Michael ; Masseron, Amandine ; Perreten, Vincent ; Nordmann, Patrice

In: Antimicrobial Agents and Chemotherapy, 2020, vol. 64, no. 2, p. -

A carbapenem-resistant Pseudomonas synxantha isolate recovered from chicken meat produced the novel carbapenemase PFM-1. That subclass B2 metallo-β- lactamase shared 71% amino acid identity with β-lactamase Sfh-1 from Serratia fonticola. The blaPFM-1 gene was chromosomally located and likely acquired. Variants of PFM-1 sharing 90% to 92% amino acid identity were identified in bacterial ...

Consortium of Swiss Academic Libraries

The carbapenemase threat in the animal world: the wrong culprit

Poirel, Laurent ; Stephan, Roger ; Perreten, Vincent ; Nordmann, Patrice

In: Journal of Antimicrobial Chemotherapy, 2014, vol. 69, no. 7, p. 2007-2008

Université de Fribourg

The carbapenemase threat in the animal world: the wrong culprit

Poirel, Laurent ; Stephan, Roger ; Perreten, Vincent ; Nordmann, Patrice

In: Journal of Antimicrobial Chemotherapy, 2014, p. -

We read with great interest two recent publications dealing with the same topic, i.e. the public health risk related to the occurrence of acquired carbapenemase-producing Gram-negative species in the animal world and the environment.1,2 Woodford et al.1 highlight the series of reports of carbapenemases found either in bacteria isolated from non-human sources or in Salmonella enterica subsp....