Université de Fribourg

The sterol-binding activity of PATHOGENESIS-RELATED PROTEIN 1 reveals the mode of action of an antimicrobial protein

Gamir, Jordi ; Darwiche, Rabih ; Hof, Pieter van't ; Choudhary, Vineet ; Stumpe, Michael ; Schneiter, Roger ; Mauch, Felix

In: The Plant Journal, 2017, vol. 89, no. 3, p. 502–509

Pathogenesis-related proteins played a pioneering role 50 years ago in the discovery of plant innate immunity as a set of proteins that accumulated upon pathogen challenge. The most abundant of these proteins, PATHOGENESIS-RELATED 1 (PR-1) encodes a small antimicrobial protein that has become, as a marker of plant immune signaling, one of the most referred to plant proteins. The biochemical...

Université de Fribourg

The chloroplast protein RPH1 plays a role in the immune response of Arabidopsis to Phytophthora brassicae

Lin, Khaoula Belhaj, Baiqing ; Mauch, Felix

In: The Plant Journal, 2009, vol. 58, no. 2, p. 287 - 298

Plant immune responses to pathogens are often associated with enhanced production of reactive oxygen species (ROS), known as the oxidative burst, and with rapid hypersensitive host cell death (the hypersensitive response, HR) at sites of attempted infection. It is generally accepted that the oxidative burst acts as a promotive signal for HR, and that HR is highly correlated with efficient disease...