Université de Fribourg

Regulatory and functional aspects of indolic metabolism in plant systemic acquired resistance

Stahl, Elia ; Bellwon, Patricia ; Huber, Stefan ; Schlaeppi, Klaus ; Bernsdorff, Friederike ; Vallat-Michel, Armelle ; Mauch, Felix ; Zeier, Jürgen

In: Molecular Plant, 2016, p. -

Tryptophan-derived, indolic metabolites possess diverse functions in Arabidopsis innate immunity to microbial pathogen infection. Here, we investigate the functional role and regulatory characteristics of indolic metabolism in Arabidopsis systemic acquired resistance (SAR) triggered by the bacterial pathogen Pseudomonas syringae. Indolic metabolism is broadly activated in both P....

Université de Fribourg

Disease resistance of Arabidopsis to Phytophthora brassicae is established by the sequential action of indole glucosinolates and camalexin

Schlaeppi, Klaus ; Abou-Mansour, Eliane ; Buchala, Antony J. ; Mauch, Felix

In: The Plant Journal, 2010, vol. 62, no. 5, p. 840 - 851

We have analysed the role of tryptophan-derived secondary metabolites in disease resistance of Arabidopsis to the oomycete pathogen Phytophthora brassicae. Transcript analysis revealed that genes encoding enzymes involved in tryptophan, camalexin and indole glucosinolate (iGS) biosynthesis are coordinately induced in response to P. brassicae. However, a deficiency in either camalexin or iGS...

Université de Fribourg

The glutathione-deficient mutant pad2-1 accumulates lower amounts of glucosinolates and is more susceptible to the insect herbivore Spodoptera littoralis

Schlaeppi, Klaus ; Bodenhausen, Natacha ; Buchala, Antony ; Mauch, Felix ; Reymond, Philippe

In: The Plant Journal, 2008, vol. 55, no. 5, p. 774 - 786

Plants often respond to pathogen or insect attack by inducing the synthesis of toxic compounds such as phytoalexins and glucosinolates (GS). The Arabidopsis mutant pad2-1 has reduced levels of the phytoalexin camalexin and is known for its increased susceptibility to fungal and bacterial pathogens. We found that pad2-1 is also more susceptible to the generalist insect Spodoptera littoralis but...