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Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, Manuel R. ; Gencer, Baris ; Adam, Luise ; Feller, Martin ; Collet, Tinh-Hai ; da Costa, Bruno R. ; Moutzouri, Elisavet ; Dopheide, Jörn ; Depairon, Michèle ; Sykiotis, Gerasimos P. ; Kearney, Patricia ; Gussekloo, Jacobijn ; Westendorp, Rudi ; Stott, David J. ; Bauer, Douglas C. ; Rodondi, Nicolas

In: The Journal of Clinical Endocrinology & Metabolism, 2018, vol. 103, no. 8, p. 2988-2997

Uptake of 99mTc-MIBI by Sclerosing Pneumocytoma Raising a False Suspicion of Metastasis From Medullary Thyroid Carcinoma

Papadakis, Georgios E. ; Tabotta, Flavian ; Levotanec, Igor ; Gonzalez, Michel ; Prior, John O. ; La Rosa, Stefano ; Sykiotis, Gerasimos P.

In: Journal of the Endocrine Society, 2018, vol. 2, no. 4, p. 386-390

An ancient founder mutation in PROKR2 impairs human reproduction

Avbelj Stefanija, Magdalena ; Jeanpierre, Marc ; Sykiotis, Gerasimos P. ; Young, Jacques ; Quinton, Richard ; Abreu, Ana Paula ; Plummer, Lacey ; Au, Margaret G. ; Balasubramanian, Ravikumar ; Dwyer, Andrew A. ; Florez, Jose C. ; Cheetham, Timothy ; Pearce, Simon H. ; Purushothaman, Radhika ; Schinzel, Albert ; Pugeat, Michel ; Jacobson-Dickman, Elka E. ; Ten, Svetlana ; Latronico, Ana Claudia ; Gusella, James F. ; Dode, Catherine ; Crowley, William F. ; Pitteloud, Nelly

In: Human Molecular Genetics, 2012, vol. 21, no. 19, p. 4314-4324

Β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue

Somm, Emmanuel ; Henry, Hugues ; Bruce, Stephen J. ; Aeby, Sébastien ; Rosikiewicz, Marta ; Sykiotis, Gerasimos P. ; Asrih, Mohammed ; Jornayvaz, François R. ; Denechaud, Pierre Damien ; Albrecht, Urs ; Mohammadi, Moosa ; Dwyer, Andrew ; Jr., James S. Acierno ; Schoonjans, Kristina ; Fajas, Lluis ; Greub, Gilbert ; Pitteloud, Nelly

In: JCI Insight, 2017, vol. 2, no. 8, p. -

β-Klotho (encoded by Klb) is the obligate coreceptor mediating FGF21 and FGF15/19 signaling. Klb–/– mice are refractory to beneficial action of pharmacological FGF21 treatment including stimulation of glucose utilization and thermogenesis. Here, we investigated the energy homeostasis in Klb–/– mice on high-fat diet in order to better understand the consequences of abrogating both...