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A comprehensive analysis of gene expression profiles in distal parts of the mouse renal tubule

Pradervand, Sylvain ; Zuber Mercier, Annie ; Centeno, Gabriel ; Bonny, Olivier ; Firsov, Dmitri

In: Pflügers Archiv - European Journal of Physiology, 2010, vol. 460, no. 6, p. 925-952

Mineralocorticoid receptor is essential for corticosteroid-induced up-regulation of L-type calcium currents in cultured neonatal cardiomyocytes

Rougier, Jean-Sébastien ; Muller, Olivier ; Berger, Stefan ; Centeno, Gabriel ; Schütz, Günther ; Firsov, Dmitri ; Abriel, Hugues

In: Pflügers Archiv - European Journal of Physiology, 2008, vol. 456, no. 2, p. 407-412

Circadian glomerular function: from physiology to molecular and therapeutical aspects

Wuerzner, Grégoire ; Firsov, Dmitri ; Bonny, Olivier

In: Nephrology Dialysis Transplantation, 2014, vol. 29, no. 8, p. 1475-1480

Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism

Michlig, Stéphanie ; Harris, Michael ; Loffing, Johannes ; Rossier, Bernard C. ; Firsov, Dmitri

In: Journal of Biological Chemistry, 2005, vol. 280, no. 46, p. 38264-38270

Activation of the mitogen-activated protein (MAP) kinase cascade by progesterone in Xenopus oocytes leads to a marked down-regulation of activity of the amiloride-sensitive epithelial sodium channel (ENaC). Here we have studied the signaling pathways involved in progesterone effect on ENaC activity. We demonstrate that: (i) the truncation of the C termini of the αβγENaC subunits...