In: Acta Applicandae Mathematica, 2006, vol. 94, no. 3, p. 195-214
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In: Positivity, 2006, vol. 10, no. 1, p. 39-49
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In: Communications in Mathematical Physics, 2004, vol. 251, no. 1, p. 1-25
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In: Acta Applicandae Mathematica, 2006, vol. 94, no. 1, p. 1-19
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In: Communications in Mathematical Physics, 2003, vol. 241, no. 1, p. 69-90
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In: Journal of Theoretical Probability, 1999, vol. 12, no. 2, p. 293-300
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In: Acta Mathematicae Applicatae Sinica, English Series, 2011, vol. 27, no. 3, p. 353-354
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In: The EMBO Journal, 2019, vol. 38, no. 7, p. e101005
DNA end resection initiates DNA break repair by homologous recombination. MRE11-RAD50-NBS1 and phosphorylated CtIP perform the first resection step by MRE11-catalyzed endonucleolytic DNA cleavage. Human NBS1, more than its Xrs2 homologue from Saccharomyces cerevisiae, is crucial for this process, highlighting complex mechanisms that regulate the MRE11 nuclease in high eukaryotes. Using a...
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In: International journal of molecular sciences, 2017, vol. 18, no. 10, p. 2042
Microtubules are the main components of mitotic spindles, and are the pillars of the cellular cytoskeleton. They perform most of their cellular functions by virtue of their unique dynamic instability processes which alternate between polymerization and depolymerization phases. This in turn is driven by a precise balance between attraction and repulsion forces between the constituents of...
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In: Proceedings of the national academy of sciences of the United States of America, 2019, vol. 116, no. 12 (March 19), p. 5505-5513
To repair DNA double-strand breaks by homologous recombination, the 5′-terminated DNA strands must first be resected to produce 3′ overhangs. Mre11 from Saccharomyces cerevisiae is a 3′ → 5′ exonuclease that is responsible for 5′ end degradation in vivo. Using plasmid-length DNA substrates and purified recombinant proteins, we show that the combined exonuclease and endonuclease...
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