Refine my results

Document type

Institution

Specific Collection

Language

Consortium of Swiss Academic Libraries

On Partially Ordered Real Involutory Algebras

Albeverio, S. ; Ayupov, Sh ; Dadakhodjayev, R.

In: Acta Applicandae Mathematica, 2006, vol. 94, no. 3, p. 195-214

Consortium of Swiss Academic Libraries

A note on moments of dividends

Albrecher, Hansjörg ; Gerber, Hans

In: Acta Mathematicae Applicatae Sinica, English Series, 2011, vol. 27, no. 3, p. 353-354

Università della Svizzera italiana

NBS1 promotes the endonuclease of the MRE11-RAD50 complex by sensing CtIP phosphorylation

Anand, Roopesh ; Jasrotia, Arti ; Bundschuh, Diana ; Howard, Sean Michael ; Ranjha, Lepakshi ; Stucki, Manuel ; Cejka, Petr

In: The EMBO Journal, 2019, vol. 38, no. 7, p. e101005

DNA end resection initiates DNA break repair by homologous recombination. MRE11-RAD50-NBS1 and phosphorylated CtIP perform the first resection step by MRE11-catalyzed endonucleolytic DNA cleavage. Human NBS1, more than its Xrs2 homologue from Saccharomyces cerevisiae, is crucial for this process, highlighting complex mechanisms that regulate the MRE11 nuclease in high eukaryotes. Using a...

Università della Svizzera italiana

Explaining the microtubule energy balance : contributions due to dipole moments, charges, van der Waals and solvation energy

Ayoub, Ahmed Taha ; Staelens, Michael ; Prunotto, Alessio ; Deriu, Marco A. ; Danani, Andrea ; Klobukowski, Mariusz ; Tuszynski, Jack Adam

In: International journal of molecular sciences, 2017, vol. 18, no. 10, p. 2042

Microtubules are the main components of mitotic spindles, and are the pillars of the cellular cytoskeleton. They perform most of their cellular functions by virtue of their unique dynamic instability processes which alternate between polymerization and depolymerization phases. This in turn is driven by a precise balance between attraction and repulsion forces between the constituents of...

Università della Svizzera italiana

Stepwise 5' DNA end-specific resection of DNA breaks by the Mre11-Rad50-Xrs2 and Sae2 nuclease ensemble

Cannavo, Elda ; Reginato, Giordano ; Cejka, Petr

In: Proceedings of the national academy of sciences of the United States of America, 2019, vol. 116, no. 12 (March 19), p. 5505-5513

To repair DNA double-strand breaks by homologous recombination, the 5′-terminated DNA strands must first be resected to produce 3′ overhangs. Mre11 from Saccharomyces cerevisiae is a 3′ → 5′ exonuclease that is responsible for 5′ end degradation in vivo. Using plasmid-length DNA substrates and purified recombinant proteins, we show that the combined exonuclease and endonuclease...