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Università della Svizzera italiana

Extreme sleep state misperception : from psychopathology to objective-subjective sleep measures

Castelnovo, Anna ; Ferri, Raffaele ; Galbiati, Andrea ; Rossi, Alessandro ; Zucconi, Marco ; Castronovo, Vincenza ; Strambi, Luigi-Ferini ; Manconi, Mauro

In: International journal of psychophysiology, 2021, vol. 167, p. 77-85

Study objectives: We tested the hypothesis that patients with extreme sleep state misperception display higher levels of psychopathology and reduced quantitative estimation abilities compared to other patients with insomnia. Secondary aims included the evaluation of group differences in subjective self-reported quality of life and sleep quality and objective sleep parameters. Methods: In this...

Università della Svizzera italiana

Space–time shape uncertainties in the forward and inverse problem of electrocardiography

Gander, Lia ; Krause, Rolf ; Multerer, Michael ; Pezzuto, Simone

In: International journal for numerical methods in biomedical engineering, 2021, vol. 37, no. 10, p. 23

In electrocardiography, the “classic” inverse problem is the reconstruction of electric potentials at a surface enclosing the heart from remote recordings at the body surface and an accurate description of the anatomy. The latter being affected by noise and obtained with limited resolution due to clinical constraints, a possibly large uncertainty may be perpetuated in the inverse ...

Università della Svizzera italiana

Head-to-head comparison of FNA cytology vs. calcitonin measurement in FNA washout fluids (FNA-CT) to diagnose medullary thyroid carcinoma : A systematic review and meta-analysis

Trimboli, Pierpaolo ; Giannelli, Jacopo ; Marques, Bernardo ; Piccardo, Arnoldo ; Crescenzi, Anna ; Deandrea, Maurilio

In: Endocrine, 2022, no. 75, p. 33–39

Purpose: The sensitivity of cytology after fine needle aspiration (FNA-cytology) in detecting medullary thyroid carcinoma (MTC) is low. To overcome this problem, measuring calcitonin (CT) in washout fluid of FNA (FNA-CT) has been largely diffused and showed good performance. However, no evidence-based study exists comparing systematically the sensitivity of FNA-cytology and FNA-CT. This study...