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Université de Fribourg

Epilepsy-associated neurocognitive disorders (EAND) in an onchocerciasis-endemic rural community in Cameroon : A population-based case–control study

K.Njamnshi, Alfred ; Chokote, Eric-Samuel ; Ngarka, Leonard ; Nfor, Leonard N. ; Tabaha, Earnest N. ; Basseguin Atchou, Jonas G. ; Angwaforbe, Samuel A. ; Nkouonlack, Cyrille ; Mengnjo, Michel K. ; Njamnshi, Wepnyu Y. ; Demaa, Fidèle ; Tataha, Godwin Y. ; Zoung-KanyiBissek, Anne-Cecile ; Annoni, Jean-Marie ; Ruffieux, Nicolas

In: Epilepsy & Behavior, 2020, vol. 112, p. 107437

Epilepsy affects at least 50 million individuals worldwide, especially in sub-Saharan Africa (sSA). Cognitive impairment is common in people with epilepsy (PWE) yet, little is known on the burden of cognitive impairment in people with epilepsy in sSA. This study was thus designed to assess cognitive impairment in PWE or epilepsy- associated neurocognitive disorders (EAND) in a rural...

Université de Fribourg

The right thalamic ventral posterolateral nucleus seems to be determinant for macrosomatognosia: a case report

ElTarhouni, Amir H. ; Beer, Laura ; Mouthon, Michael ; Erni, Britt ; Aellen, Jerome ; Annoni, Jean-Marie ; Accolla, Ettore ; Dieguez, Sebastian ; Chabwine, Joelle N.

In: BMC Neurology, 2020, vol. 20, no. 1, p. 393

Background: Macrosomatognosiais the illusory sensation of a substantially enlarged body part. This disorder of the body schema, also called “Alice in wonderland syndrome” is still poorly understood and requires careful documentation and analysis of cases. The patient presented here is unique owing to his unusual macrosomatognosia phenomenology, but also given the unreported localization...

Université de Fribourg

Are people with aphasia (pwa) involved in the creation of quality of life and aphasia impact-related questionnaires? A scoping review

Charalambous, Marina ; Kambanaros, Maria ; Annoni, Jean-Marie

In: Brain Sciences, 2020, vol. 10, no. 10, p. 688

Background: Quality of Life (QoL) questionnaires are used to describe the impact of aphasia on stroke survivors’ life. People with aphasia (PWA) are traditionally excluded from research, potentially leading to a mismatch between the factors chosen in the tools and the realistic needs of PWA. The purpose of this review was to determine the direct involvement of PWA in the creation of QoL and...

Université de Fribourg

Effects of theta burst stimulation over the dorsolateral prefrontal cortex on language switching – A behavioral and ERP study

Pestalozzi, Maria I. ; Annoni, Jean-Marie ; Müri, René M. ; Jost, Lea B.

In: Brain and Language, 2020, vol. 205, p. 104775

This study investigated the role of the left dorsolateral prefrontal cortex (DLPFC) in language switching using theta burst stimulation (TBS) and electroencephalography in late bilinguals. After a sham-controlled baseline, participants received either excitatory or inhibitory TBS over the left DLPFC before conducting picture naming tasks in pure language blocks and a language switching...

Université de Fribourg

Embodied semantics in a second language: critical review and clinical implications

Monaco, Elisa ; Jost, Lea B. ; Gygax, Pascal M. ; Annoni, Jean-Marie

In: Frontiers in Human Neuroscience, 2019, vol. 13, p. -

The role of the sensorimotor system in second language (L2) semantic processing as well as its clinical implications for bilingual patients has hitherto been neglected. We offer an overview of the issues at stake in this under-investigated field, presenting the theoretical and clinical relevance of studying L2 embodiment and reviewing the few studies on this topic. We highlight that (a) the...

Université de Fribourg

Auditory time perception in Huntington’s disease

Vez, S. ; Köhli, J. ; Frey, B. ; Magezi, David A. ; Annoni, Jean-Marie ; Burgunder, J.-M.

In: Neuropsychologia, 2018, vol. 119, p. 247–252

Huntington's disease (HD) is characterized by early involvement of the striatum. It affects the pace of repetitive motor activity, as motor timing depends on basal ganglia activity. However, data are lacking on the impact of this process on auditory time perception in motor non-affected gene carriers.Objective: This work aims to test the performance in time perception of a group of mutation...

Université de Fribourg

Investigating post-stroke fatigue: An individual participant data meta-analysis

B.Cumming, Toby ; Yeo, Ai Beng ; Marquez, Jodie ; Churilov, Leonid ; Annoni, Jean-Marie ; Badaru, Umaru ; Ghotbi, Nastaran ; Harbison, Joe ; Kwakkel, Gert ; Lerdal, Anners ; Mills, Roger ; Naess, Halvor ; Nyland, Harald ; Schmid, Arlene ; Tang, Wai Kwong ; Tseng, Benjamin ; Port, Ingridvan de ; Mead, Gillian ; English, Coralie

In: Journal of Psychosomatic Research, 2018, vol. 113, p. 107–112

The prevalence of post-stroke fatigue differs widely across studies, and reasons for such divergence are unclear. We aimed to collate individual data on post-stroke fatigue from multiple studies to facilitate high-powered meta-analysis, thus increasing our understanding of this complex phenomenon.Methods: We conducted an Individual Participant Data (IPD) meta-analysis on post-stroke fatigue...

Université de Fribourg

Multimodal communication in aphasia: perception and production of co-speech gestures during face-to-face conversation

Preisig, Basil C. ; Eggenberger, Noëmi ; Cazzoli, Dario ; Nyffeler, Thomas ; Gutbrod, Klemens ; Annoni, Jean-Marie ; Meichtry, Jurka R. ; Nef, Tobias ; Müri, René M.

In: Frontiers in Human Neuroscience, 2018, vol. 12, p. -

The role of nonverbal communication in patients with post-stroke language impairment (aphasia) is not yet fully understood. This study investigated how aphasic patients perceive and produce co-speech gestures during face-to-face interaction, and whether distinct brain lesions would predict the frequency of spontaneous co-speech gesturing. For this purpose, we recorded samples of conversations...

Université de Fribourg

Dorsolateral prefrontal transcranial direct current stimulation modulates language processing but does not facilitate overt second language word production

Radman, Narges ; Britz, Juliane ; Buetler, Karin ; Weekes, Brendan S. ; Spierer, Lucas ; Annoni, Jean-Marie

In: Frontiers in Neuroscience, 2018, vol. 12, p. -

Word retrieval in bilingual speakers partly depends on executive-control systems in the left prefrontal cortex - including dorsolateral prefrontal cortex (DLPFC). We tested the hypothesis that DLPFC modulates word production of words specifically in a second language (L2) by measuring the effects of anodal transcranial direct current stimulation (anodal-tDCS) over the DLPFC on picture naming...