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Université de Neuchâtel

Wirkungsweise und Effekte sozialer Unterstützung in Ausbildung und Schule

Hofmann, Claudia ; Tschan, Franziska (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2016.

The transition from school to work is one of the major developmental tasks for young adults and has important consequences for further career development. It is also a particular challenge for young people with learning difficulties. Social support is considered to be an important facilitating factor in early career development and is therefore particularly important for these young people. In...

Université de Neuchâtel

Impacts of urban gardening on soil quality, soil fauna and soil multifunctionality

Tresch, Simon ; Le Bayon, Claire (Dir.) ; Fliessbach, Andreas (Codir.) ; Moretti, Marco (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

Urban gardens are important and at the same time popular greenspaces. As urban areas are expanding globally, urban gardens play an increasingly important role in contributing to essential ecosystem services, well-being of citizens, and biodiversity in a city. Gardening activities determine above- and belowground diversity of plants and insects. However, the effect of gardening activities on soil...

Université de Fribourg

Medical and long-term care with endogenous health and longevity

Schünemann, Johannes ; Strulik, Holger ; Trimborn, Timo

(Working Papers SES ; 505, revised)

For the population over 65, long-term care (LTC) expenditure constitutes a considerable share in total health expenditures. In this paper, we distinguish between medical care, intended to improve one›s state of health, and personal care required for daily routine. Personal care can be either carried out autonomously or by a third party. In the course of aging, autonomous personal care is...

Université de Fribourg

Specific eccentric–isokinetic cluster training improves static strength elements on rings for elite gymnasts

Schärer, Christoph ; Tacchelli, Lisa ; Göpfert, Beat ; Gross, Micah ; Lüthy, Fabian ; Taube, Wolfgang ; Hübner, Klaus

In: International Journal of Environmental Research and Public Health, 2019, vol. 16, no. 22, p. 4571

In gymnastics, coaches are constantly searching for efficient training methods in order to improve the athletes’ performance. Therefore, in this study we aimed to investigate the effects of a novel, four-week, gymnastic-specific, eccentric–isokinetic (0.1 m/s) cluster training on a computer-controlled training device on the improvement of two static strength elements on rings (swallow and...

Université de Fribourg

Evaluating a sensitive issue: reliability of a clinical evaluation for allodynia severity

Packham, Tara L. ; Spicher, Claude J. ; MacDermid, Joy C. ; Quintal, Isabelle ; Buckley, Norman

In: Somatosensory & Motor Research, 2019, p. 1–6

Allodynia is a common feature of neuropathic pain with few validated clinical evaluation options. We identified a need to estimate the measurement properties of the standardised evaluation procedure for static mechanical allodynia severity popularised by the somatosensory rehabilitation of pain method, known as the rainbow pain scale. This study (www.clinicaltrials.gov. NCT02070367) undertook...

Université de Fribourg

Modulation of calretinin expression in human mesothelioma cells reveals the implication of the fak and wnt signaling pathways in conferring chemoresistance towards cisplatin

Wörthmüller, Janine ; Salicio, Valérie ; Oberson, Anne ; Blum, Walter ; Schwaller, Beat

In: International Journal of Molecular Sciences, 2019, vol. 20, no. 21, p. 5391

Malignant mesothelioma (MM) is an aggressive asbestos-linked neoplasm, characterized by dysregulation of signaling pathways. Due to intrinsic or acquired chemoresistance, MM treatment options remain limited. Calretinin is a Ca2+-binding protein expressed during MM tumorigenesis that activates the FAK signaling pathway, promoting invasion and epithelial-to-mesenchymal transition. Constitutive...

Université de Fribourg

The relationship between linguistic ability, multilingualism, and dementia

van den Noort, Maurits ; Vermeire, Katrien ; Staudte, Heike ; Perriard, Benoît ; Bosch, Peggy ; Lim, Sabina

In: Journal of Alzheimer’s Disease, 2019, vol. 72, no. 4, p. 1041–1044

In a recent article of the Journal of Alzheimer’s Disease, Hack et al. (2019) argue that linguistic ability rather than multilingualism is a significant predictor of dementia. In their longitudinal study, they investigated 325 religious sisters who were older than 75 years of age. Self-reports were used in order to determine multilingualism. They found that speaking two or three languages...

Université de Fribourg

Low-load blood flow restriction training induces similar morphological and mechanical Achilles tendon adaptations compared with high-load resistance training

Centner, Christoph ; Lauber, Benedikt ; Seynnes, Olivier R. ; Jerger, Simon ; Sohnius, Tim ; Gollhofer, Albert ; König, Daniel

In: Journal of Applied Physiology, 2019, vol. 127, no. 6, p. 1660–1667

ow-load blood flow restriction (LL-BFR) training has gained increasing interest in the scientific community by demonstrating that increases in muscle mass and strength are comparable to conventional high-load (HL) resistance training. Although adaptations on the muscular level are well documented, there is little evidence on how LL-BFR training affects human myotendinous properties....

Université de Fribourg

Cost-effectiveness of drug-eluting stents in elderly patients with coronary artery disease: the SENIOR trial

Bulsei, Julie ; Butel, Thibault ; Varenne, Olivier ; Cook, Stéphane ; Cuisset, Thomas ; Carrié, Didier ; Hovasse, Thomas ; Morice, Marie-Claude ; Sinnaeve, Peter R. ; Durand-Zaleski, Isabelle

In: Value in Health, 2019, vol. 22, no. 12, p. 1355–1361

Elderly patients receive bare metal stents instead of drug-eluting stents (DES) to shorten the duration of dual antiplatelet therapy (DAPT). The SENIOR trial compared outcomes between these 2 types of stents combined with a short duration of DAPT. A significant decrease in the number of patients with at least 1 major adverse cardiac and cerebrovascular event (MACCE) was noted in the DES...