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Consortium of Swiss Academic Libraries

Surgery Versus Radiotherapy for Early Oropharyngeal Tumors: a Never-Ending Debate

Monnier, Yan ; Simon, Christian

In: Current Treatment Options in Oncology, 2015, vol. 16, no. 9, p. 1-13

Consortium of Swiss Academic Libraries

Breast cancer and pregnancy

Knabben, Laura ; Mueller, Michel D.

In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -

Université de Fribourg

Magi1, a new potential tumor suppressor gene in estrogen receptor positive breast cancer

Alday-Parejo, Begoña ; Richard, François ; Wörthmüller, Janine ; Rau, Tilman ; Galván, José A. ; Desmedt, Christine ; Santamaria-Martinez, Albert ; Rüegg, Curzio

In: Cancers, 2020, vol. 12, no. 1, p. 223

Membrane-associated guanylate kinase (MAGUK) with inverted domain structure-1 (MAGI1) is an intracellular adaptor protein that stabilizes epithelial junctions consistent with a tumor suppressive function in several cancers of epithelial origin. Here we report, based on experimental results and human breast cancer (BC) patients’ gene expression data, that MAGI1 is highly expressed and acts...

Université de Fribourg

Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)—hydrogen sulfide (H2S) pathway in cancer cells

Augsburger, Fiona ; Szabo, Csaba

In: Pharmacological Research, 2020, vol. 154, p. 104083

Hydrogen sulfide (H2S), produced by various endogenous enzyme systems, serves various biological regulatory roles in mammalian cells in health and disease. Over recent years, a new concept emerged in the field of H2S biology, showing that various cancer cells upregulate their endogenous H2S production, and utilize this mediator in autocrine and paracrine manner to stimulate proliferation,...