Ergebnisse einschränken

Development of a murine vertical transmission model for Toxoplasma gondii oocyst infection and studies on the efficacy of bumped kinase inhibitor (BKI)-1294 and the naphthoquinone buparvaquone against congenital toxoplasmosis

Müller, Joachim ; Aguado-Martínez, Adriana ; Ortega-Mora, Luis-Miguel ; Moreno-Gonzalo, Javier ; Ferre, Ignacio ; Hulverson, Matthew A. ; Choi, Ryan ; McCloskey, Molly C. ; Barrett, Lynn K. ; Maly, Dustin J. ; Ojo, Kayode K. ; Van Voorhis, Wes ; Hemphill, Andrew

In: Journal of Antimicrobial Chemotherapy, 2017, vol. 72, no. 8, p. 2334-2341

Reply to Planet et al

François, Patrice ; von Dach, Elodie ; Diene, Seydina M. ; Harbarth, Stephan ; Schrenzel, Jacques

In: The Journal of Infectious Diseases, 2016, vol. 214, no. 10, p. 1610-1611

The Swiss Transplant Cohort Study: Lessons from the First 6Years

Berger, Christoph ; Bochud, Pierre-Yves ; Boggian, Katja ; Cusini, Alexia ; Egli, Adrian ; Garzoni, Christian ; Hirsch, Hans ; Hoffmann, Matthias ; Khanna, Nina ; Manuel, Oriol ; Meylan, Pascal ; Nadal, David ; van Delden, Christian ; Weisser, Maja ; Mueller, Nicolas

In: Current Infectious Disease Reports, 2015, vol. 17, no. 6, p. 1-5

A phage-based decolonisation strategy against pan-resistant enterobacterial strains

Poirel, Laurent ; Nordmann, Patrice ; Ortiz de la Rosa, José Manuel ; Kutateladze, Mzia ; Gatermann, Sören ; Corbellino, Mario

In: The Lancet Infectious Diseases, 2020, vol. 20, no. 5, p. 525–526

Efficacy of dual carbapenem treatment in a murine sepsis model of infection due to carbapenemase-producing Acinetobacter baumannii

Cebrero-Cangueiro, T. ; Nordmann, Patrice ; Carretero-Ledesma, M. ; Pachón, J. ; Pachón-Ibáñez, M. E.

In: Journal of Antimicrobial Chemotherapy, 2020, p. dkaa487

Objectives: To evaluate the in vivo efficacy of a dual carbapenem combination containing imipenem plus meropenem against carbapenem-resistant Acinetobacter baumannii producing carbapenemases OXA-23 or OXA-58.Methods: An experimental model of peritonitis using C57BL/6J female mice was developed and the minimum lethal doses were calculated for infections due to OXA-23 or OXA-58 producers of A. ...

Emergence of colistin-resistant Gram-negative Enterobacterales in the gut of patients receiving oral colistin and neomycin decontamination

Lastours, Victoire de ; Poirel, Laurent ; Huttner, Benedikt ; Harbarth, Stephan ; Denamur, Erick ; Nordmann, Patrice

In: Journal of Infection, 2020, vol. 80, no. 5, p. 578–606

Identification and structure of a multidonor class of head-directed influenza-neutralizing antibodies reveal the mechanism for its recurrent elicitation

Sao-Fong Cheung, Crystal ; Fruehwirth, Alexander ; Paparoditis, Philipp Carl Georg ; Shen, Chen-Hsiang ; Foglierini, Mathilde ; Joyce, M. Gordon ; Leung, Kwanyee ; Piccoli, Luca ; Rawi, Reda ; Silacci-Fregni, Chiara ; Tsybovsky, Yaroslav ; Verardi, Raffaello ; Wang, Lingshu ; Wang, Shuishu ; Yang, Eun Sung ; Zhang, Baoshan ; Zhang, Yi ; Chuang, Gwo-Yu ; Corti, Davide ; Mascola, John R. ; Shapiro, Lawrence ; Kwong, Peter D. ; Lanzavecchia, Antonio ; Zhou, Tongqing

In: Cell reports, 2020, vol. 32, no. 9, p. 12 p

Multidonor antibodies are of interest for vaccine design because they can in principle be elicited in the general population by a common set of immunogens. For influenza, multidonor antibodies have been observed against the hemagglutinin (HA) stem, but not the immunodominant HA head. Here, we identify and characterize a multidonor antibody class (LPAF-a class) targeting the HA head. This class...

3D imaging of undissected optically cleared Anopheles stephensi mosquitoes and midguts infected with Plasmodium parasites

Niz, Mariana De ; Kehrer, Jessica ; Brancucci, Nicolas M. B. ; Moalli, Federica ; Reynaud, Emmanuel G. ; Stein, Jens V. ; Frischknecht, Friedrich

In: PLOS ONE, 2020, vol. 15, no. 9, p. e0238134

Malaria is a life-threatening disease, caused by Apicomplexan parasites of the Plasmodium genus. The Anopheles mosquito is necessary for the sexual replication of these parasites and for their transmission to vertebrate hosts, including humans. Imaging of the parasite within the insect vector has been attempted using multiple microscopy methods, most of which are hampered by the presence of...

Swiss consensus recommendations on urinary tract infections in children

Buettcher, Michael ; Trueck, Johannes ; Niederer-Loher, Anita ; Heininger, Ulrich ; Agyeman, Philipp ; Asner, Sandra ; Berger, Christoph ; Bielicki, Julia ; Kahlert, Christian ; Kottanattu, Lisa ; Meyer Sauteur, Patrick M. ; Paioni, Paolo ; Posfay-Barbe, Klara ; Relly, Christa ; Ritz, Nicole ; Zimmermann, Petra ; Zucol, Franziska ; Gobet, Rita ; Shavit, Sandra ; Rudin, Christoph ; Laube, Guido ; von Vigier, Rodo ; Neuhaus, Thomas J.

In: European Journal of Pediatrics, 2020, p. -

The kidneys and the urinary tract are a common source of infection in children of all ages, especially infants and young children. The main risk factors for sequelae after urinary tract infections (UTI) are congenital anomalies of the kidney and urinary tract (CAKUT) and bladder-bowel dysfunction. UTI should be considered in every child with fever without a source. The differentiation between...

Odontoid osteomyelitis in children: illustrative case reports and review of the literature

Zimmermann, Petra ; Ritz, Nicole ; Stranzinger, Enno

In: The Pediatric Infectious Disease Journal, 2016, vol. 35, no. 8, p. 920–923