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On the Efficiency of NHS Ester Cross-Linkers for Stabilizing Integral Membrane Protein Complexes

Chen, Fan ; Gerber, Sabina ; Korkhov, Volodymyr ; Mireku, Samantha ; Bucher, Monika ; Locher, Kaspar ; Zenobi, Renato

In: Journal of The American Society for Mass Spectrometry, 2015, vol. 26, no. 3, p. 493-498

How do ethanolamine plasmalogens contribute to order and structure of neurological membranes?

West, Ana ; Zoni, Valeria ; Teague, Walter E. ; Leonard, Alison N. ; Vanni, Stefano ; Gawrisch, Klaus ; Tristram-Nagle, Stephanie ; Sachs, Jonathan N. ; Klauda, Jeffery B.

In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 5, p. 828–839

Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here we report on mixed bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-(1Z-...

High-Mass MALDI-MS Using Ion Conversion Dynode Detectors: Influence of the Conversion Voltage on Sensitivity and Spectral Quality

Weidmann, Simon ; Zenobi, Renato

In: Journal of The American Society for Mass Spectrometry, 2014, vol. 25, no. 6, p. 950-954

Quantification of Saquinavir from Lysates of Peripheral Blood Mononuclear Cells Using Microarrays and Standard MALDI-TOF-MS

Pabst, Martin ; Fagerer, Stephan ; Köhling, Rudolf ; Eyer, Klaus ; Krismer, Jasmin ; Jefimovs, Konstantins ; Ibáñez, Alfredo ; Zenobi, Renato

In: Journal of The American Society for Mass Spectrometry, 2014, vol. 25, no. 6, p. 1083-1086

Templated assembly of pore-forming peptides in lipid membranes

Fennouri, Aziz ; List, Jonathan ; Dupasquier, Jessica ; Haeni, Laetitia ; Vanni, Stefano ; Rothen-Rutishauser, Barbara ; Mayer, Michael

In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 59–62

Pore-forming peptides are of interest due to their antimicrobial activity and ability to form gateways through lipid membranes. Chemical modification of these peptides makes it possible to arrange several peptide monomers into well-defined pore-forming structures using various templating strategies. These templated super-structures can exert antimicrobial activity at significantly lower total...

Bimetallic metal organic frameworks with precisely positioned metal centers for efficient H2 storage

Kim, Daeok ; Song, Kyung Seob ; Buyukcakir, Onur ; Yildirim, Taner ; Coskun, Ali

In: Chemical Communications, 2018, vol. 54, no. 86, p. 12218–12221

We demonstrated that the ratio and position of two different metal ions, Pd and Cu, can be precisely controlled within MOFs through predesigned metal clusters. These MOF structures incorporating Pd–Cu paddle wheel units were synthesised simply by reacting Pd–Cu acetate metal clusters and tritopic organic linkers at room temperature. Pd–Cu open metal sites were found to be uniformly...

Synthesis of telechelic poly(p-benzamide)s

Alizadeh, Mahshid ; Kilbinger, Andreas F. M.

In: Macromolecules, 2018, vol. 51, no. 11, p. 4363–4369

Well-defined telechelic poly(benzamide)s were synthesized by chain-growth polycondensation of phenyl-4-amino benzoate and pentafluorophenyl-4-amino benzoate derivatives with a bifunctional initiator in the presence of LiTMP as base. The polymerization was carried out at −70 °C to prevent self-initiated polymerization. To confirm the control over molecular weight, different defined...

Membrane protein dynamics in different environments: simulation study of the outer membrane protein X in a lipid bilayer and in a micelle

Choutko, Alexandra ; Glättli, Alice ; Fernández, César ; Hilty, Christian ; Wüthrich, Kurt ; van Gunsteren, Wilfred

In: European Biophysics Journal, 2011, vol. 40, no. 1, p. 39-58

Assessing the value of CAN-gene mutations using MALDI-TOF MS

Kohler, Corina ; Tavelin, Björn ; Fan, Alex ; Radpour, Ramin ; Barekati, Zeinab ; Levi, Fabio ; Zhong, Xiao ; Lenner, Per ; Toniolo, Paolo

In: Journal of Cancer Research and Clinical Oncology, 2011, vol. 137, no. 8, p. 1239-1244

Simultaneous sampling of volatile and non-volatile analytes in beer for fast fingerprinting by extractive electrospray ionization mass spectrometry

Zhu, Liang ; Hu, Zhong ; Gamez, Gerardo ; Law, Wai ; Chen, HuanWen ; Yang, ShuiPing ; Chingin, Konstantin ; Balabin, Roman ; Wang, Rui ; Zhang, TingTing ; Zenobi, Renato

In: Analytical and Bioanalytical Chemistry, 2010, vol. 398, no. 1, p. 405-413