In: Journal of Inherited Metabolic Disease, 2015, vol. 38, no. 6, p. 1007-1019
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In: Journal of Inherited Metabolic Disease, 2015, vol. 38, no. 5, p. 863-872
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In: Methods in Ecology and Evolution, 2020, vol. -, no. -, p. -
raxmlGUI is a graphical user interface to RAxML, one of the most popular and widely used softwares for phylogenetic inference using maximum likelihood.Here we present raxmlGUI 2.0, a complete rewrite of the GUI which seamlessly integrates RAxML binaries for all major operating systems with an intuitive graphical front‐end to setup and run phylogenetic analyses.Our program offers automated...
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In: Proceedings of the National Academy of Sciences, 2020, vol. 117, no. 42, p. 26281–26287
The biological interchange between North and South America associated with the formation of the Isthmus of Panama is key to defining current gradients of species diversity. A major gap in our understanding of the interchange is its asymmetry, where mammals of North American origin attained higher diversity in South America than vice versa. The prevailing view is that this asymmetry resulted...
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In: Ecography, 2020/n/a/n/a/-
Geo-referenced species occurrences from public databases have become essential to biodiversity research and conservation. However, geographical biases are widely recognized as a factor limiting the usefulness of such data for understanding species diversity and distribution. In particular, differences in sampling intensity across a landscape due to differences in human accessibility are...
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In: Science Advances, 2020, vol. 6, no. 36, p. eabb2313
To understand the current biodiversity crisis, it is crucial to determine how humans have affected biodiversity in the past. However, the extent of human involvement in species extinctions from the Late Pleistocene onward remains contentious. Here, we apply Bayesian models to the fossil record to estimate how mammalian extinction rates have changed over the past 126,000 years, inferring...
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In: Proceedings of the Royal Society B: Biological Sciences, 2020, vol. 287, no. 2020-1931, p. 20201162
The extinction of species can destabilize ecological processes. A way to assess the ecological consequences of species loss is by examining changes in functional diversity. The preservation of functional diversity depends on the range of ecological roles performed by species, or functional richness, and the number of species per role, or functional redundancy. However, current knowledge is...
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In: Nature communications, 2017, vol. 8, p. 1600
We have previously reported the molecular signature of murine pathogenic TH17 cells that induce experimental autoimmune encephalomyelitis (EAE) in animals. Here we show that human peripheral blood IFN-γ+IL-17+ (TH1/17) and IFN-γ−IL-17+ (TH17) CD4+ T cells display distinct transcriptional profiles in high-throughput transcription analyses. Compared to TH17 cells, TH1/17 cells have gene...
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In: Journal of Inherited Metabolic Disease, 2014, vol. 37, no. 5, p. 831-840
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In: Clinical Chemistry and Laboratory Medicine (CCLM), 2016, vol. 54, no. 10, p. 1655-1661
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