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Université de Fribourg

Evaluation of the potential of cobalamin derivatives bearing ru(ii) polypyridyl complexes as photosensitizers for photodynamic therapy

Jakubaszek, Marta ; Rossier, Jeremie ; Karges, Johannes ; Delasoie, Joachim ; Goud, Bruno ; Gasser, Gilles ; Zobi, Fabio

In: Helvetica Chimica Acta, 2019, vol. 102, no. 7, p. -

The current photosensitizers (PSs) for photodynamic therapy (PDT) lack selectivity for cancer cells. To tackle this drawback, in view of selective cancer delivery, we envisioned conjugating two ruthenium polypyridyl complexes to vitamin B12 (Cobalamin, Cbl) to take advantage of the solubility and active uptake of the latter. Ultimately, our results showed that the transcobalamin pathway is...

Consortium of Swiss Academic Libraries

Current status of anti-vascular endothelial growth factor therapy in Europe

Wolf, Sebastian

In: Japanese Journal of Ophthalmology, 2008, vol. 52, no. 6, p. 433-439

Consortium of Swiss Academic Libraries

Macular pigment density at the site of altered fundus autofluorescence

Rothenbuehler, Simon ; Wolf-Schnurrbusch, Ute ; Wolf, Sebastian

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2011, vol. 249, no. 4, p. 499-504

Consortium of Swiss Academic Libraries

Macular pigment measurements: which method should we use?

Wolf, Sebastian

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2006, vol. 244, no. 12, p. 1562-1564

Consortium of Swiss Academic Libraries

Multimodal imaging in macular diagnostics: combined OCT-SLO improves therapeutical monitoring

Brinkmann, Christian ; Wolf, Sebastian ; Wolf-Schnurrbusch, Ute

In: Graefe's Archive for Clinical and Experimental Ophthalmology, 2008, vol. 246, no. 1, p. 9-16