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Consortium of Swiss Academic Libraries

Network simulations to study seed exchange for agrobiodiversity conservation

Pautasso, Marco

In: Agronomy for Sustainable Development, 2015, vol. 35, no. 1, p. 145-150

Université de Fribourg

Cell cycle constraints and environmental control of local DNA hypomethylation in α-proteobacteria

Ardissone, Silvia ; Redder, Peter ; Russo, Giancarlo ; Frandi, Antonio ; Fumeaux, Coralie ; Patrignani, Andrea ; Schlapbach, Ralph ; Falquet, Laurent ; Viollier, Patrick H.

In: PLOS Genetics, 2016, vol. 12, no. 12, p. e1006499

Heritable DNA methylation imprints are ubiquitous and underlie genetic variability from bacteria to humans. In microbial genomes, DNA methylation has been implicated in gene transcription, DNA replication and repair, nucleoid segregation, transposition and virulence of pathogenic strains. Despite the importance of local (hypo)methylation at specific loci, how and when these patterns are...

Università della Svizzera italiana

An MVA vector expressing HIV-1 envelope under the control of a potent vaccinia virus promoter as a promising strategy in HIV/AIDS vaccine design

Pérez, Patricia ; Marín, María Q. ; Lázaro-Frías, Adrián ; Sorzano, Carlos Óscar S. ; Di Pilato, Mauro ; Gómez, Carmen E. ; Esteban, Mariano ; García-Arriaza, Juan

In: Vaccines, 2019, vol. 7, no. 4, p. 208

Highly attenuated poxviral vectors, such as modified vaccinia virus ankara (MVA), are promising vaccine candidates against several infectious diseases. One of the approaches developed to enhance the immunogenicity of poxvirus vectors is increasing the promoter strength and accelerating during infection production levels of heterologous antigens. Here, we have generated and characterized the ...

Université de Fribourg

Biocontrol activity of three Pseudomonas in a newly assembled collection of Phytophthora infestans isolates

De Vrieze, Mout ; Gloor, Ramona ; Massana Codina, Josep ; Torriani, Stefano ; Gindro, Katia ; L?Haridon, Floriane ; Bailly, Aurélien ; Weisskopf, Laure

In: Phytopathology, 2019, vol. 109, no. 9, p. 1555–1565

Late blight caused by the oomycete Phytophthora infestans constitutes the greatest threat to potato production worldwide. Considering the increasing concerns regarding the emergence of novel fungicide-resistant genotypes and the general demand for reducing inputs of synthetic and copper-based fungicides, the need for alternative control methods is acute. Several bacterial antagonists have...

Università della Svizzera italiana

Regulatory control of DNA end resection by Sae2 phosphorylation

Cannavo, Elda ; Johnson, Dominic ; Andres, Sara N. ; Kissling, Vera M. ; Reinert, Julia K. ; Garcia, Valerie ; Erie, Dorothy A. ; Hess, Daniel ; Thomä, Nicolas H. ; Enchev, Radoslav I. ; Peter, Matthias ; Williams, R. Scott ; Neale, Matt J. ; Cejka, Petr

In: Nature communications, 2018, vol. 9, p. 4016

DNA end resection plays a critical function in DNA double-strand break repair pathway choice. Resected DNA ends are refractory to end-joining mechanisms and are instead channeled to homology-directed repair. Using biochemical, genetic, and imaging methods, we show that phosphorylation of Saccharomyces cerevisiae Sae2 controls its capacity to promote the Mre11-Rad50-Xrs2 (MRX) nuclease to...

Université de Fribourg

Microbial life in the grapevine: what can we expect from the leaf microbiome?

Vionnet, Léo ; Vrieze, Mout De ; Dutartre, Agnès ; Gfeller, Aurélie ; Lüthi, Angelika ; L’Haridon, Floriane ; Weisskopf, Laure

In: OENO One, 2018, vol. 52, no. 3, p. 219–224

Recent studies have shown that plants harbor complex bacterial communities, the so- called “microbiome”. We are only beginning to unravel the origin of these bacterial plant inhabitants, their community structure and their roles, which, in analogy to the gut microbiome, are likely to be of essential nature. The aim of this work was to analyze the abundance and diversity of the cultivable...

Consortium of Swiss Academic Libraries

RNA turnover and chromatin-dependent gene silencing

Bühler, Marc

In: Chromosoma, 2009, vol. 118, no. 2, p. 141-151