Consortium of Swiss Academic Libraries

The role of the acquired immune response in systemic sclerosis

Chizzolini, Carlo ; Boin, Francesco

In: Seminars in Immunopathology, 2015, vol. 37, no. 5, p. 519-528

Consortium of Swiss Academic Libraries

Sialic acids in cancer biology and immunity

Pearce, Oliver M T. ; Läubli, Heinz

In: Glycobiology, 2016, vol. 26, no. 2, p. 111-128

Université de Fribourg

Granzyme B attenuates bacterial virulence by targeting secreted factors

López León, Diego ; Matthey, Patricia ; Fellay, Isabelle ; Blanchard, Marianne ; Martinvalet, Denis ; Mantel, Pierre-Yves ; Filgueira, Luis ; Walch, Michael

In: iScience, 2020, vol. 23, no. 3, p. 100932

Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show that granzyme B degrades multiple secreted virulence mediators from Listeria monocytogenes,...