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Wounding of Arabidopsis halleri leaves enhances cadmium accumulation that acts as a defense against herbivory

Plaza, Sonia ; Weber, Johann ; Pajonk, Simone ; Thomas, Jérôme ; Talke, Ina ; Schellenberg, Maja ; Pradervand, Sylvain ; Burla, Bo ; Geisler, Markus ; Martinoia, Enrico ; Krämer, Ute

In: BioMetals, 2015, vol. 28, no. 3, p. 521-528

Altered Sleep Homeostasis in Rev-erbα Knockout Mice

Mang, Géraldine M. ; La Spada, Francesco ; Emmenegger, Yann ; Chappuis, Sylvie ; Ripperger, Jürgen A. ; Albrecht, Urs ; Franken, Paul

In: Sleep, 2016, vol. 39, no. 3, p. 589-601

GLUT2, glucose sensing and glucose homeostasis

Thorens, Bernard

In: Diabetologia, 2015, vol. 58, no. 2, p. 221-232

From the Cover: High Susceptibility of Lrig1 Sebaceous Stem Cells to TCDD in Mice

Fontao, Fabienne ; Barnes, Laurent ; Kaya, Guerkan ; Saurat, Jean-Hilaire ; Sorg, Olivier

In: Toxicological Sciences, 2017, vol. 160, no. 2, p. 230-243

Ins1 Cre knock-in mice for beta cell-specific gene recombination

Thorens, Bernard ; Tarussio, David ; Maestro, Miguel ; Rovira, Meritxell ; Heikkilä, Eija ; Ferrer, Jorge

In: Diabetologia, 2015, vol. 58, no. 3, p. 558-565

Conserved functions of ether lipids and sphingolipids in the early secretory pathway

Jiménez-Rojo, Noemi ; Leonetti, Manuel D. ; Zoni, Valeria ; Colom, Adai ; Feng, Suihan ; Iyengar, Namrata R. ; Matile, Stefan ; Roux, Aurélien ; Vanni, Stefano ; Weissman, Jonathan S. ; Riezman, Howard

In: Current Biology, 2020, vol. 30, no. 19, p. 3775-3787.e7

Sphingolipids play important roles in physiology and cell biology, but a systematic examination of their functions is lacking. We performed a genome-wide CRISPRi screen in sphingolipid-depleted human cells and identified hypersensitive mutants in genes of membrane trafficking and lipid biosynthesis, including ether lipid synthesis. Systematic lipidomic analysis showed a coordinate regulation...

The role of TNFR2 and DR3 in the in vivo expansion of tregs in T cell depleting transplantation regimens

Rodriguez-Barbosa, Jose-Ignacio ; Schneider, Pascal ; Graca, Luis ; Bühler, Leo ; Perez-Simon, Jose-Antonio ; Rio, Maria-Luisa del

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 9, p. 3347

Regulatory T cells (Tregs) are essential for the maintenance of tolerance to self and non-self through cell-intrinsic and cell-extrinsic mechanisms. Peripheral Tregs survival and clonal expansion largely depend on IL-2 and access to co-stimulatory signals such as CD28. Engagement of tumor necrosis factor receptor (TNFR) superfamily members, in particular TNFR2 and DR3, contribute to promote...

Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development

Winnik, Stephan ; Gaul, Daniel ; Preitner, Frédéric ; Lohmann, Christine ; Weber, Julien ; Miranda, Melroy ; Liu, Yilei ; van Tits, Lambertus ; Mateos, José ; Brokopp, Chad ; Auwerx, Johan ; Thorens, Bernard ; Lüscher, Thomas ; Matter, Christian

In: Basic Research in Cardiology, 2014, vol. 109, no. 1, p. 1-15

Hepatic glucose sensing and integrative pathways in the liver

Oosterveer, Maaike ; Schoonjans, Kristina

In: Cellular and Molecular Life Sciences, 2014, vol. 71, no. 8, p. 1453-1467

Immunological aspects of atherosclerosis

Garrido-Urbani, S. ; Meguenani, M. ; Montecucco, F. ; Imhof, B.

In: Seminars in Immunopathology, 2014, vol. 36, no. 1, p. 73-91