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Università della Svizzera italiana

A psychometric analysis of the Daily Drinking Questionnaire in a nationally representative sample of young adults from a Mediterranean drinking culture

Piumatti, G. ; Aresi, G. ; Marta, E.

In: Journal of ethnicity in substance abuse, 2021, p. 1-19

Aims: To examine psychometric properties of the Daily Drinking Questionnaire (DDQ) in a Mediterranean “wet” drinking culture. Methods: Three studies were conducted using random samples drawn from a representative sample of Italian young adults (N¼5,955; females ¼ 62%; mean age ¼ 27): Study 1 explored the factorial structure of weekly alcohol consumption; in Study 2 multi-group...

Università della Svizzera italiana

Immigration policy and immigrants' sleep : evidence from DACA

Giuntella, Osea ; Lonsky, Jakub ; Mazzonna, Fabrizio ; Stella, Luca

In: Journal of economic behavior and organization, 2021, vol. 182, no. February, p. 12 p

Stress is associated with sleep problems and poor sleep is linked to mental health and depression symptoms. The stress associated with immigrant status and immigration policy can directly affect mental health. While previous studies have documented the significant relationship between immigration policy and the physical and mental health of immigrants, we know little about the effects of...

Université de Fribourg

Genome-based characterization of two Colombian clinical Providencia rettgeri isolates co-harboring NDM-1, VIM-2, and other β-lactamases

Piza-Buitrago, Adriana ; Rincón, Verónica ; Donato, John ; Saavedra, Sandra Yamile ; Duarte, Carolina ; Morero, Jaime ; Falquet, Laurent ; Reguero, María Teresa ; Barreto-Hernández, Emiliano

In: BMC Microbiology, 2020, vol. 20, no. 1, p. 345

Providencia rettgeri is a nosocomial pathogen associated with urinary tract infections and related to Healthcare-Associated Infection (HAI). In recent years isolates producing New Delhi Metallo-β-lactamase (NDM) and other β-lactamases have been reported that reduce the efficiency of clinical antimicrobial treatments. In this study, we analyzed antibiotic resistance, the presence of...

Université de Fribourg

A novel study on the inhibitory effect of marine macroalgal extracts on hyphal growth and biofilm formation of candidemia isolates

El-Zawawy, Nessma A. ; El-Shenody, Rania A. ; Ali, Sameh S. ; El-Shetehy, Mohamed

In: Scientific Reports, 2020, vol. 10, no. 1, p. 9339

Biofilm formation and hyphal growth are considered to be the most serious virulence factors of Candida species in blood causing candidemia infections, which are difficult to treat due to the spread of resistant Candida isolates to most antifungal drugs. Therefore, in this study, we investigated the effect of different types and concentrations of selected macroalgal extracts from Cladostephus...

Università della Svizzera italiana

Antigen-specific Th17 cells are primed by distinct and complementary dendritic cell subsets in oropharyngeal candidiasis

Trautwein-Weidner, Kerstin ; Gladiator, André ; Kirchner, Florian R. ; Becattini, Simone ; Rülicke, Thomas ; Sallusto, Federica ; LeibundGut-Landmann, Salomé

In: PLoS pathogens, 2015, vol. 11, no. 10, p. e1005164

Candida spp. can cause severe and chronic mucocutaneous and systemic infections in immunocompromised individuals. Protection from mucocutaneous candidiasis depends on T helper cells, in particular those secreting IL-17. The events regulating T cell activation and differentiation toward effector fates in response to fungal invasion in different tissues are poorly understood. Here we generated...

Université de Fribourg

Silver(I) complexes with 4,7-phenanthroline efficient in rescuing the zebrafish embryos of lethal Candida albicans infection

Pavic, Aleksandar ; Savić, Nada D. ; Glišić, Biljana Đ. ; Crochet, Aurélien ; Vojnovic, Sandra ; Kurutos, Atanas ; Stanković, Dalibor M. ; Fromm, Katharina M. ; Nikodinovic-Runic, Jasmina ; Djuran, Miloš I.

In: Journal of Inorganic Biochemistry, 2019, vol. 195, p. 149–163

Five novel silver(I) complexes with 4,7-phenanthroline (4,7-phen), [Ag(NO3-O)(4,7- phen-μ-N4,N7)]n (1), [Ag(ClO4-О)(4,7-phen-μ-N4,N7)]n (2), [Ag(CF3COO-O)(4,7- phen-μ-N4,N7)]n (3), [Ag2(H2O)0.58(4,7-phen)3](SbF6)2 (4) and {[Ag2(H2O)(4,7- phen-μ-N4,N7)2](BF4)2}n (5) were synthesized, structurally elucidated and biologically evaluated. These complexes showed selectivity towards Candida spp....