In: Journal of Antimicrobial Chemotherapy, 2018, vol. 73, no. 12, p. 3413-3422
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In: European Journal of Pediatrics, 2015, vol. 174, no. 10, p. 1347-1355
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In: International Journal for Quality in Health Care, 2017, vol. 29, no. 4, p. 527-533
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In: Medizinische Klinik - Intensivmedizin und Notfallmedizin, ///-
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In: Frontiers in Immunology, 2020, vol. 11, p. -
Malaria infection caused by the Plasmodium species is a complex disease in which a fine balance between host and parasite factors determine the outcome of the disease. While in some individuals, the infection will trigger only a mild and uncomplicated disease, other individuals will develop severe complications and eventually die. Extracellular vesicles (EVs) secreted by infected red blood...
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In: Pathogens, 2020, vol. 9, no. 1, p. 21
Microglia are the chief immune cells of the brain and have been reported to be activated in severe malaria. Their activation may drive towards neuroinflammation in cerebral malaria. Malaria-infected red blood cell derived-extracellular vesicles (MiREVs) are produced during the blood stage of malaria infection. They mediate intercellular communication and immune regulation, among other...
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In: Nature Communications, 2019, vol. 10, no. 1, p. 1369
Methods to diagnose malaria are of paramount interest to eradicate the disease. Current methods have severe limitations, as they are either costly or not sensitive enough to detect low levels of parasitemia. Here we report an ultrasensitive, yet low- resource chemical assay for the detection and quantification of hemozoin, a biomarker of all Plasmodium species. Solubilized hemozoin catalyzes...
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In: JoVE (Journal of Visualized Experiments), 2018, no. 132, p. e57067
Malaria is a life-threatening disease caused by Plasmodium parasites, with P. falciparum being the most prevalent on the African continent and responsible for most malaria-related deaths globally. Several factors including parasite sequestration in tissues, vascular dysfunction, and inflammatory responses influence the evolution of the disease in malaria-infected people. P. falciparum-infected...
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In: World Journal of Surgery, 2009, vol. 33, no. 3, p. 558-566
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In: Infection, 2005, vol. 33, no. 1, p. 33-35
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