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The atmospheric monitoring system of the JEM-EUSO instrument

Adams Jr., J. ; Ahmad, S. ; Albert, J. ; Allard, D. ; Anchordoqui, L. ; Andreev, V. ; Anzalone, A. ; Arai, Y. ; Asano, K. ; Ave Pernas, M. ; Baragatti, P. ; Barrillon, P. ; Batsch, T. ; Bayer, J. ; Bechini, R. ; Belenguer, T. ; Bellotti, R. ; Belov, K. ; Berlind, A. ; Bertaina, M. ; Biermann, P. ; Biktemerova, S. ; Blaksley, C. ; Blanc, N. ; Błȩcki, J. ; Blin-Bondil, S. ; Blümer, J. ; Bobik, P. ; Bogomilov, M. ; Bonamente, M. ; Briggs, M. ; Briz, S. ; Bruno, A. ; Cafagna, F. ; Campana, D. ; Capdevielle, J. ; Caruso, R. ; Casolino, M. ; Cassardo, C. ; Castellinic, G. ; Catalano, C. ; Catalano, G. ; Cellino, A. ; Chikawa, M. ; Christl, M. ; Cline, D. ; Connaughton, V. ; Conti, L. ; Cordero, G. ; Crawford, H. ; Cremonini, R. ; Csorna, S. ; Dagoret-Campagne, S. ; de Castro, A. ; De Donato, C. ; de la Taille, C. ; De Santis, C. ; del Peral, L. ; Dell'Oro, A. ; De Simone, N. ; Di Martino, M. ; Distratis, G. ; Dulucq, F. ; Dupieux, M. ; Ebersoldt, A. ; Ebisuzaki, T. ; Engel, R. ; Falk, S. ; Fang, K. ; Fenu, F. ; Fernández-Gómez, I. ; Ferrarese, S. ; Finco, D. ; Flamini, M. ; Fornaro, C. ; Franceschi, A. ; Fujimoto, J. ; Fukushima, M. ; Galeotti, P. ; Garipov, G. ; Geary, J. ; Gelmini, G. ; Giraudo, G. ; Gonchar, M. ; González Alvarado, C. ; Gorodetzky, P. ; Guarino, F. ; Guzmán, A. ; Hachisu, Y. ; Harlov, B. ; Haungs, A. ; Hernández Carretero, J. ; Higashide, K. ; Ikeda, D. ; Ikeda, H. ; Inoue, N. ; Inoue, S. ; Insolia, A. ; Isgrò, F. ; Itow, Y. ; Joven, E. ; Judd, E. ; Jung, A. ; Kajino, F. ; Kajino, T. ; Kaneko, I. ; Karadzhov, Y. ; Karczmarczyk, J. ; Karus, M. ; Katahira, K. ; Kawai, K. ; Kawasaki, Y. ; Keilhauer, B. ; Khrenov, B. ; Kim, J. ; Kim, S. ; Kim, S. ; Kleifges, M. ; Klimov, P. ; Kolev, D. ; Kreykenbohm, I. ; Kudela, K. ; Kurihara, Y. ; Kusenko, A. ; Kuznetsov, E. ; Lacombe, M. ; Lachaud, C. ; Lee, J. ; Licandro, J. ; Lim, H. ; López, F. ; Maccarone, M. ; Mannheim, K. ; Maravilla, D. ; Marcelli, L. ; Marini, A. ; Martinez, O. ; Masciantonio, G. ; Mase, K. ; Matev, R. ; Medina-Tanco, G. ; Mernik, T. ; Miyamoto, H. ; Miyazaki, Y. ; Mizumoto, Y. ; Modestino, G. ; Monaco, A. ; Monnier-Ragaigne, D. ; Morales de los Ríos, J. ; Moretto, C. ; Morozenko, V. ; Mot, B. ; Murakami, T. ; Murakami, M. Nagano ; Nagata, M. ; Nagataki, S. ; Nakamura, T. ; Napolitano, T. ; Naumov, D. ; Nava, R. ; Neronov, A. ; Nomoto, K. ; Nonaka, T. ; Ogawa, T. ; Ogio, S. ; Ohmori, H. ; Olinto, A. ; Orleański, P. ; Osteria, G. ; Panasyuk, M. ; Parizot, E. ; Park, I. ; Park, H. ; Pastircak, B. ; Patzak, T. ; Paul, T. ; Pennypacker, C. ; Perez Cano, S. ; Peter, T. ; Picozza, P. ; Pierog, T. ; Piotrowski, L. ; Piraino, S. ; Plebaniak, Z. ; Pollini, A. ; Prat, P. ; Prévôt, G. ; Prieto, H. ; Putis, M. ; Reardon, P. ; Reyes, M. ; Ricci, M. ; Rodríguez, I. ; Rodríguez Frías, M. ; Ronga, F. ; Roth, M. ; Rothkaehl, H. ; Roudil, G. ; Rusinov, I. ; Rybczyński, M. ; Sabau, M. ; Sáez-Cano, G. ; Sagawa, H. ; Saito, A. ; Sakaki, N. ; Sakata, M. ; Salazar, H. ; Sánchez, S. ; Santangelo, A. ; Santiago Crúz, L. ; Sanz Palomino, M. ; Saprykin, O. ; Sarazin, F. ; Sato, H. ; Sato, M. ; Schanz, T. ; Schieler, H. ; Scotti, V. ; Segreto, A. ; Selmane, S. ; Semikoz, D. ; Serra, M. ; Sharakin, S. ; Shibata, T. ; Shimizu, H. ; Shinozaki, K. ; Shirahama, T. ; Siemieniec-Oziȩbło, G. ; Silva López, H. ; Sledd, J. ; Słomińska, K. ; Sobey, A. ; Sugiyama, T. ; Supanitsky, D. ; Suzuki, M. ; Szabelska, B. ; Szabelski, J. ; Tajima, F. ; Tajima, N. ; Tajima, T. ; Takahashi, Y. ; Takami, H. ; Takeda, M. ; Takizawa, Y. ; Tenzer, C. ; Tibolla, O. ; Tkachev, L. ; Tokuno, H. ; Tomida, T. ; Tone, N. ; Toscano, S. ; Trillaud, F. ; Tsenov, R. ; Tsunesada, Y. ; Tsuno, K. ; Tymieniecka, T. ; Uchihori, Y. ; Unger, M. ; Vaduvescu, O. ; Valdés-Galicia, J. ; Vallania, P. ; Valore, L. ; Vankova, G. ; Vigorito, C. ; Villaseñor, L. ; von Ballmoos, P. ; Wada, S. ; Watanabe, J. ; Watanabe, S. ; Watts Jr, J. ; Weber, M. ; Weiler, T. ; Wibig, T. ; Wiencke, L. ; Wille, M. ; Wilms, J. ; Włodarczyk, Z. ; Yamamoto, T. ; Yamamoto, Y. ; Yang, J. ; Yano, H. ; Yashin, I. ; Yonetoku, D. ; Yoshida, K. ; Yoshida, S. ; Young, R. ; Zotov, M. ; Zuccaro Marchi, A.

In: Experimental Astronomy, 2015, vol. 40, no. 1, p. 45-60

Université de Fribourg

High colonization rate and heterogeneity of ESBL- and carbapenemase-producing enterobacteriaceae isolated from gull feces in Lisbon, Portugal

Aires-de-Sousa, Marta ; Fournier, Claudine ; Lopes, Elizeth ; Lencastre, Hermínia de ; Nordmann, Patrice ; Poirel, Laurent

In: Microorganisms, 2020, vol. 8, no. 10, p. 1487

In order to evaluate whether seagulls living on the Lisbon coastline, Portugal, might be colonized and consequently represent potential spreaders of multidrug-resistant bacteria, a total of 88 gull fecal samples were screened for detection of extended- spectrum β-lactamase (ESBL)- or carbapenemase-producing Enterobacteriaceae for methicillin-resistant Staphylococcus aureus (MRSA) and for...

Université de Fribourg

Epidemiology of carbapenemase-producing Klebsiella pneumoniae in northern Portugal: Predominance of KPC-2 and OXA-48

Lopes, Elizeth ; Saavedra, Maria José ; Costa, Eliana ; Lencastre, Hermíniade ; Poirel, Laurent ; Aires-de-Sousa, Marta

In: Journal of Global Antimicrobial Resistance, 2020, vol. 22, p. 349–353

Objectives: To provide, for the first time, data on the molecular epidemiology of carbapenemase-producing Klebsiella pneumoniae clinical isolates from the northern region of Portugal (Trás-os-Montes and Alto Douro).Methods: A total of 106 carbapenemase-producing K. pneumoniae isolates recovered from clinical samples and rectal swabs between January 2018 and March 2019 were included in this...

Université de Fribourg

Lipid nanoparticles biocompatibility and cellular uptake in a 3D human lung model

Magalhães, Joana ; Pinheiro, Marina ; Drasler, Barbara ; Septiadi, Dedy ; Petri-Fink, Alke ; Santos, Susana G ; Rothen-Rutishauser, Barbara ; Reis, Salette

In: Nanomedicine, 2020, vol. 15, no. 3, p. 259–271

Aim: Design nanostructured lipid carriers (NLC) to facilitate drug delivery to tuberculosis-infected areas, exploiting macrophage mannose receptors and assess their uptake in a 3D human lung model. Materials & methods: NLCs and mannosylated-NLCs were synthetized and characterized. Their uptake and biocompatibility were tested in a 3D human lung model. Results: The formulations have...

Université de Fribourg

Detailed detection of active layer freeze-thaw dynamics using quasi-continuous electrical resistivity tomography (Deception Island, Antarctica)

Farzamian, Mohammad ; Vieira, Gonçalo ; Santos, Fernando A. Monteiro ; Tabar, Borhan Yaghoobi ; Hauck, Christian ; Paz, Maria Catarina ; Bernardo, Ivo ; Ramos, Miguel ; Pablo, Miguel Angel de

In: The Cryosphere, 2020, vol. 14, no. 3, p. 1105–1120

Climate-induced warming of permafrost soils is a global phenomenon, with regional and site-specific variations which are not fully understood. In this context, a 2-D automated electrical resistivity tomography (A-ERT) system was installed for the first time in Antarctica at Deception Island, associated to the existing Crater Lake site of the Circumpolar Active Layer Monitoring – South ...

Università della Svizzera italiana

Arl13b regulates breast cancer cell migration and invasion by controlling integrin-mediated signaling

Casalou, Cristina ; Faustino, Alexandra ; Silva, Fernanda ; Ferreira, Inês C. ; Vaqueirinho, Daniela ; Ferreira, Andreia ; Castanheira, Pedro ; Barona, Teresa ; Ramalho, José S. ; Serpa, Jacinta ; Félix, Ana ; Barral, Duarte C.

In: Cancers, 2019, vol. 11, no. 10, p. 1461

Breast cancer is the first cause of cancer-related mortality among women worldwide, according to the most recent estimates. This mortality is mainly caused by the tumors’ ability to form metastases. Cancer cell migration and invasion are essential for metastasis and rely on the interplay between actin cytoskeleton remodeling and cell adhesion. Therefore, understanding the mechanisms by which...

Université de Fribourg

Intestinal carriage of extended-spectrum beta-lactamase–producing Enterobacteriaceae at admission in a Portuguese hospital

Aires-de-Sousa, Marta ; Lopes, Elizeth ; Gonçalves, Maria Luísa ; Pereira, Ana Luísa ; Machado e Costa, Augusto ; Lencastre, Hermínia de ; Poirel, Laurent

In: European Journal of Clinical Microbiology & Infectious Diseases, 2019, p. -

To evaluate the prevalence of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae fecal carriers at admission in a Portuguese hospital and to determine the epidemiology and antimicrobial resistance patterns of ESBL-producing isolates. During a 2-month period, rectal swabs were collected at hospital admission from 151 at-risk patients. In addition, 48 rectal swabs were...

Università della Svizzera italiana

Role of CXCL13 and CCL20 in the recruitment of B cells to inflammatory foci in chronic arthritis

Armas-González, Estefanía ; Domínguez-Luis, María Jesús ; Díaz-Martín, Ana ; Arce-Franco, Mayte ; Castro-Hernández, Javier ; Danelon, Gabriela ; Hernández-Hernández, Vanesa ; Bustabad-Reyes, Sagrario ; Cantabrana, Alberto ; Uguccioni ; Díaz-González, Federico

In: Arthritis research & therapy, 2018, vol. 20, p. 114

Background: B cells exert their pathogenic action in rheumatoid arthritis (RA) locally in the synovium. This study was undertaken to elucidate the chemokines responsible for the recruitment of B cells in the inflamed synovium, taking into account that the rich chemokine milieu present in the synovial tissue can fine-tune modulate discrete chemokine receptors. Methods: Expression levels of...