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Université de Fribourg

Compartment and cell-type specific hypoxia responses in the developing Drosophila brain

Baccino-Calace, Martin ; Prieto, Daniel ; Cantera, Rafael ; Egger, Boris

In: Biology Open, 2020, vol. 9, no. 8, p. -

Environmental factors such as the availability of oxygen are instructive cues that regulate stem cell maintenance and differentiation. We used a genetically encoded biosensor to monitor the hypoxic state of neural cells in the larval brain of Drosophila. The biosensor reveals brain compartment and cell-type specific levels of hypoxia. The values correlate with differential tracheolation that...

Université de Fribourg

Hypoxia enhances endothelial intercellular adhesion molecule 1 protein level through upregulation of arginase type II and mitochondrial oxidative stress

Liang, Xiujie ; Arullampalam, Prakash ; Yang, Zhihong ; Ming, Xiu-Fen

In: Frontiers in Physiology, 2019, vol. 10, p. -

Hypoxia plays a crucial role in the pathogenesis of cardiovascular diseases. Mitochondrial enzyme arginase type II (Arg-II) is reported to lead to endothelial dysfunction and enhance the expression of endothelial inflammatory adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1). In this study, we investigate the role of Arg-II in...

Consortium of Swiss Academic Libraries

Stem cells for brain repair in neonatal hypoxia-ischemia

Chicha, L. ; Smith, T. ; Guzman, R.

In: Child's Nervous System, 2014, vol. 30, no. 1, p. 37-46

Consortium of Swiss Academic Libraries

The fetal brain: role of progesterone and allopregnanolone

Pluchino, Nicola ; Russo, Marinella ; Genazzani, Andrea R.

In: Hormone Molecular Biology and Clinical Investigation, 2016, vol. 27, no. 1, p. 29-34X

Consortium of Swiss Academic Libraries

Current status of anti-vascular endothelial growth factor therapy in Europe

Wolf, Sebastian

In: Japanese Journal of Ophthalmology, 2008, vol. 52, no. 6, p. 433-439

Consortium of Swiss Academic Libraries

The Mammary Gland Vasculature Revisited

Andres, Anne-Catherine ; Djonov, Valentin

In: Journal of Mammary Gland Biology and Neoplasia, 2010, vol. 15, no. 3, p. 319-328