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Università della Svizzera italiana

Targeting the DNA damage response for patients with lymphoma : preclinical and clinical evidences

Carrassa, Laura ; Colombo, Ilaria ; Damia, Giovanna ; Bertoni, Francesco

In: Cancer treatment reviews, 2020, vol. 90, p. 11

The DNA damage response (DDR) is a well-coordinated cellular network activated by DNA damage. The unravelling of the key players in DDR, their specific inactivation in different tumor types and the synthesis of specific chemical inhibitors of DDR represent a new hot topic in cancer therapy. In this article, we will review the importance of DDR in lymphoma development and how this can be...

Università della Svizzera italiana

Phase angle is associated with length of hospital stay, readmissions, mortality, and falls in patients hospitalized in internal-medicine wards : a retrospective cohort study

Del Giorno, Rosaria ; Quarenghi, Massimo ; Stefanelli, Kevyn ; Rigamonti, Alice ; Stanglini, Carlotta ; De Vecchi, Valentina ; Gabutti, Luca

In: Nutrition, 2021, vol. 85, no. May, p. 7 p

The aim of this study was to investigate the predictive value of bioimpedance phase angle (PA) on selected clinical outcomes in patients hospitalized in internal-medicine wards. This was a retrospective observational study of 168 patients admitted to the internalmedicine service (52.9% women, 47.1% men), with a mean (± SD) age of 73.9 ± 15.9 y. Anthropometric examination, laboratory tests,...

Consortium of Swiss Academic Libraries

Breast cancer and pregnancy

Knabben, Laura ; Mueller, Michel D.

In: Hormone Molecular Biology and Clinical Investigation, 2017, vol. 32, no. 1, p. -