In: Acta Neurochirurgica, 2008, vol. 150, no. 7, p. 729-731
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In: Molecular Neurobiology, 2003, vol. 27, no. 1, p. 73-98
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In: Brain, 2005, vol. 128, no. 2, p. 356-364
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In: Brain, 2008, vol. 131, no. 7, p. 1776-1782
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In: Cerebral Cortex, 2004, vol. 14, no. 11, p. 1276-1286
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In: European Journal of Neuroscience, 2012, vol. 35, no. 10, p. 1622-1629
The aim of the present study was to artificially induce plasticity in the human spinal cord and evaluate whether this plasticity is pathway specific. For this purpose, a technique called paired associative stimulation (PAS) was applied. Volleys evoked by transcranial magnetic stimulation over the primary motor cortex and peripheral nerve stimulation of the nervus tibialis in the popliteal...
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In: The Journal of Comparative Neurology, 2007, vol. 502, no. 4, p. 644 - 659
After injury, regrowth of axons in mammalian adult central nervous system is highly limited. However, in monkeys subjected to unilateral cervical lesion (C7-C8 level), neutralization of an important neurite outgrowth inhibitor, Nogo-A, stimulated axonal sprouting caudal to the lesion, accompanied by enhanced functional recovery of manual dexterity, compared with lesioned monkeys treated with a...
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In: Journal of Neurotrauma, 2005, vol. 22(6), p. 703
The effects of a unilateral interruption of the dorsolateral funiculus at cervical level on the survival of neurons in the motor cortex were investigated in macaque monkeys. The lesion was made on the left side at the transition region between the 7th and 8th cervical segments, above the motoneurons controlling hand muscles. As a result, the homolateral hand became paretic,...
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In: Brain Research, 2004, vol. 1017, p. 172-182
After a sub-total hemisection of the cervical cord at level C7/C8 in monkeys, a paralysis of the homolateral hand is rapidly followed by an incomplete recovery of manual dexterity, reaching a plateau after about 40–50 days, whose extent appears related to the size of the lesion. During a few days after the lesion, the hand representation in the contralateral motor cortex disappeared, replaced...
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