Affiner les résultats

Cardiovascular dysfunction in children conceived by assisted reproductive technologies

Scherrer, Urs ; Rexhaj, Emrush ; Allemann, Yves ; Sartori, Claudio ; Rimoldi, Stefano F.

In: European Heart Journal, 2015, vol. 36, no. 25, p. 1583-1589

Perspectives of targeting mTORC1–S6K1 in cardiovascular aging

Ming, Xiu-Fen ; Montani, Jean-Pierre ; Yang, Zhihong

In: Frontiers in Vascular Physiology, 2012, vol. 3, p. 5

The global population aging is accelerating and age-associated diseases including cardiovascular diseases become more challenging. The underlying mechanisms of aging and age-associated cardiovascular dysfunction remain elusive. There are substantial evidences demonstrating a pivotal role of the mammalian target of rapamycin complex 1 (mTORC1) and its down-stream effector S6K1 signaling in...