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Nitrous oxide does not produce a clinically important sparing effect during closed-loop delivered propofol-remifentanil anaesthesia guided by the bispectral index: a randomized multicentre study†‡

Liu, N. ; Le Guen, M. ; Boichut, N. ; Genty, A. ; Hérail, T. ; Schmartz, D. ; Khefif, G. ; Landais, A. ; Bussac, J. J. ; Charmeau, A. ; Baars, J. ; Rehberg, B. ; Tricoche, S. ; Chazot, T. ; Sessler, D. I. ; Fischler, M. ; Struys, M. M. R. F. ; Struys, M. M. R. F.

In: British Journal of Anaesthesia, 2014, vol. 112, no. 5, p. 842-851