Affiner les résultats

Risk prediction in early phases of clinical trial protocol design

Perritaz, Alex ; Teodoro, Douglas (Dir.)

Mémoire de master : Haute école de gestion de Genève, 2020 ; MASID 107.

The purpose of this study is to develop a solution able to determine the validity of a specific protocol before moving to a new stage of the clinical trial. This makes it possible to rule out ineffective protocols and to preserve financial resources. While the risks associated with the clinical trial design lead to substantial savings, they also prevent effective and promising drugs from...

Antibody-based immunotherapy for ovarian cancer: where are we at?

Tse, B. W. C. ; Collins, A. ; Oehler, M. K. ; Zippelius, A. ; Heinzelmann-Schwarz, V. A.

In: Annals of Oncology, 2014, vol. 25, no. 2, p. 322-331

Development of appropriateness criteria for colonoscopy: comparison between a standardized expert panel and an evidence-based medicine approach

NICOLLIER-FAHRNI, ANNE ; VADER, JOHN-PAUL ; FROEHLICH, FLORIAN ; GONVERS, JEAN-JACQUES ; BURNAND, BERNARD

In: International Journal for Quality in Health Care, 2003, vol. 15, no. 1, p. 15-022

Consensus recommendations for a standardized Brain Tumor Imaging Protocol in clinical trials

Ellingson, Benjamin M. ; Bendszus, Martin ; Boxerman, Jerrold ; Barboriak, Daniel ; Erickson, Bradley J. ; Smits, Marion ; Nelson, Sarah J. ; Gerstner, Elizabeth ; Alexander, Brian ; Goldmacher, Gregory ; Wick, Wolfgang ; Vogelbaum, Michael ; Weller, Michael ; Galanis, Evanthia ; Kalpathy-Cramer, Jayashree ; Shankar, Lalitha ; Jacobs, Paula ; Pope, Whitney B. ; Yang, Dewen ; Chung, Caroline ; Knopp, Michael V. ; Cha, Soonme ; van den Bent, Martin J. ; Chang, Susan ; Al Yung, W.K. ; Cloughesy, Timothy F. ; Wen, Patrick Y. ; Gilbert, Mark R. ; Whitney, Andrew ; Sandak, David ; Musella, Al ; Haynes, Chas ; Wallace, Max ; Arons, David F. ; Kingston, Ann ; Sul, Joohee ; Krainak, Daniel ; Ellingson, Benjamin M. ; Bendszus, Martin ; Boxerman, Jerrold ; Barboriak, Daniel ; Erickson, Bradley J. ; Smits, Marion ; Nelson, Sarah J. ; Gerstner, Elizabeth ; Alexander, Brian ; Goldmacher, Gregory ; Wick, Wolfgang ; Vogelbaum, Michael ; Weller, Michael ; Galanis, Evanthia ; Kalpathy-Cramer, Jayashree ; Shankar, Lalitha ; Jacobs, Paula ; Pope, Whitney B. ; Yang, Dewen ; Chung, Caroline ; Knopp, Michael V. ; Cha, Soonme ; van den Bent, Martin J. ; Chang, Susan ; Al Yung, W.K. ; Cloughesy, Timothy F. ; Wen, Patrick Y. ; Gilbert, Mark R. ; Whitney, Andrew ; Sandak, David ; Musella, Al ; Haynes, Chas ; Wallace, Max ; Arons, David F. ; Kingston, Ann ; Sul, Joohee ; Krainak, Daniel

In: Neuro-Oncology, 2015, vol. 17, no. 9, p. 1188-1198

Twenty-two points to consider for clinical trials in systemic sclerosis, based on EULAR standards

Khanna, Dinesh ; Furst, Daniel E. ; Allanore, Yannick ; Bae, Sangmee ; Bodukam, Vijay ; Clements, Philip J. ; Cutolo, Maurizio ; Czirjak, Laszlo ; Denton, Christopher P. ; Distler, Oliver ; Walker, Ulrich A. ; Matucci-Cerinic, Marco ; Müller-Ladner, Ulf ; Seibold, James R. ; Singh, Manjit ; Tyndall, Alan

In: Rheumatology, 2015, vol. 54, no. 1, p. 144-151

Repair of the injured spinal cord, a joint approach of basic and clinical research

Buchli, Anita D. ; Rouiller, Eric M. ; Mueller, Roland ; Dietz, Volker ; Schwab, Martin E.

In: Neurodegenerative Diseases, 2007, vol. 4, no. 1, p. 51-56

The myelin protein Nogo-A is a potent inhibitor of neurite outgrowth in the central nervous system, thus contributing to the incapacity of fiber tracts in the adult spinal cord to regenerate after injury. In this review we report on a joint approach of different research groups to develop a therapy applying anti-Nogo-A antibodies to the injured spinal cord. While basic researchers took the...