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Università della Svizzera italiana

Identification and structure of a multidonor class of head-directed influenza-neutralizing antibodies reveal the mechanism for its recurrent elicitation

Sao-Fong Cheung, Crystal ; Fruehwirth, Alexander ; Paparoditis, Philipp Carl Georg ; Shen, Chen-Hsiang ; Foglierini, Mathilde ; Joyce, M. Gordon ; Leung, Kwanyee ; Piccoli, Luca ; Rawi, Reda ; Silacci-Fregni, Chiara ; Tsybovsky, Yaroslav ; Verardi, Raffaello ; Wang, Lingshu ; Wang, Shuishu ; Yang, Eun Sung ; Zhang, Baoshan ; Zhang, Yi ; Chuang, Gwo-Yu ; Corti, Davide ; Mascola, John R. ; Shapiro, Lawrence ; Kwong, Peter D. ; Lanzavecchia, Antonio ; Zhou, Tongqing

In: Cell reports, 2020, vol. 32, no. 9, p. 12 p

Multidonor antibodies are of interest for vaccine design because they can in principle be elicited in the general population by a common set of immunogens. For influenza, multidonor antibodies have been observed against the hemagglutinin (HA) stem, but not the immunodominant HA head. Here, we identify and characterize a multidonor antibody class (LPAF-a class) targeting the HA head. This class...

Università della Svizzera italiana

Collaborating with complementary and alternative medicine (CAM) providers when writing HPV vaccine review articles

Deml, Michael J. ; Dietrich, Léna G. ; Wingeier, Bernhard ; Etter, Gisela ; Gallmann, Caesar ; Berger, Christoph ; Suggs, L. Suzanne ; Huber, Benedikt M. ; Tarr, Philip E.

In: Journal of clinical medicine, 2020, vol. 9, no. 2, p. 15 p

Novel strategies are needed to address vaccine hesitancy (VH), which correlates with complementary and alternative medicine (CAM). In Switzerland, CAM providers play important roles in vaccine counseling of vaccine hesitant (VH) parents, and traditional vaccination messaging tends to overlook CAM provider perspectives. In the setting of a Swiss national research program on VH, our key strategy ...

Consortium of Swiss Academic Libraries

Changing Face of Vaccination in Immunocompromised Hosts

O'Shea, Daire ; Widmer, Lukas ; Stelling, Jörg ; Egli, Adrian

In: Current Infectious Disease Reports, 2014, vol. 16, no. 9, p. 1-11

Consortium of Swiss Academic Libraries

Immunization in children with chronic renal failure: a practical approach

Neuhaus, Thomas

In: Pediatric Nephrology, 2004, vol. 19, no. 12, p. 1334-1339