Consortium of Swiss Academic Libraries

Posterior Cortical Atrophy: Review of the Recent Literature

Borruat, François-Xavier

In: Current Neurology and Neuroscience Reports, 2013, vol. 13, no. 12, p. 1-8

Université de Fribourg

Notch1 hallmarks fibrillary depositions in sporadic Alzheimer’s disease

Brai, Emanuele ; Raio, Noemi Alina ; Alberi, Lavinia

In: Acta Neuropathologica Communications, 2016, vol. 4, p. 64

Background: Notch1 signaling is a cellular cascade with a fundamental role from brain development to adult brain function. Reduction in Notch1 affects synaptic plasticity, memory and olfaction. On the other hand, Notch1 overactivation after brain injury is detrimental for neuronal survival. Some familial Alzheimer’s disease (FAD) mutations in Presenilins can affect Notch1...