Consortium of Swiss Academic Libraries

The calyx of Held

Schneggenburger, Ralf ; Forsythe, Ian

In: Cell and Tissue Research, 2006, vol. 326, no. 2, p. 311-337

Université de Fribourg

Motor axonal sprouting and neuromuscular junction loss in an animal model of Charcot-Marie-Tooth disease

Ang, Eng-Tat ; Schafer, Ralf ; Baltensperger, Richard ; Wernig, Anton ; Celio, Marco ; Sancho Oliver, Sara

In: Journal of Neuropathology & Experimental Neurology, 2010, vol. 69, no. 3, p. 281-293

Muscle weakness in Charcot-Marie-Tooth Type 1A disease (CMT1A) caused by mutations in peripheral myelin protein 22 (PMP22) has been attributed to an axonopathy that results in denervation and muscle atrophy. The underlying pathophysiological mechanisms involved are not understood. We investigated motor performance, neuromuscular junctions (NMJs), physiological parameters, and muscle morphometry...