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Krebsbehandlung mit Antisense-Molekülen : Wissenschaftliche Aspekte und klinische Perspektiven = Antisense molecules for targeted cancer therapy : Scientific aspects and clinical perspectives

Zangemeister-Wittke, U.

Coexistence of copy number increases of c-Myc, ZNF217, CCND1, ErbB1 and ErbB2 in ovarian cancers

Dimova, Ivanka ; Raicheva, Sashka ; Dimitrov, Rumen ; Doganov, Nikolai ; Toncheva, Draga

In: Onkologie, 2009, vol. 32, no. 7, p. 405-410

Background: We selected 5 oncogenes with well-established roles in carcinogenesis – CCND1, ErbB1, ErbB2, c-mycand ZNF217– to investigate the coexistence of their copy imbalances in relation to the clinico-pathological characteristics of ovarian tumors. Materials and Methods: Fluorescence in situ hybridization for the 5 genes was applied to a preexisting tissue microarray. 38 ovarian tumors...