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Epigenetik bei entzündlichen Systemerkrankungen = Epigenetics in inflammatory systemic diseases

Ospelt, C. ; Gay, S.

miR-146a and NF-κB1 regulate mast cell survival and T lymphocyte differentiation

Rusca, Nicole ; Dehò, Lorenzo ; Montagner, Sara ; Zielinski, Christina E. ; Sica, Antonio ; Sallusto, Federica ; Monticelli, Silvia

In: Molecular and cellular biology, 2012, vol. 32, no. 21, p. 4432-4444

The transcription factor NF-κB regulates the expression of a broad number of genes central to immune and inflammatory responses. We identified a new molecular network that comprises specifically the NF-κB family member NF-κB1 (p50) and miR-146a, and we show that in mast cells it contributes to the regulation of cell homeostasis and survival, while in T lymphocytes it modulates T cell...

Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

Nesca, Valeria ; Guay, Claudiane ; Jacovetti, Cécile ; Menoud, Véronique ; Peyot, Marie-Line ; Laybutt, D. ; Prentki, Marc ; Regazzi, Romano

In: Diabetologia, 2013, vol. 56, no. 10, p. 2203-2212

Deciphering microRNA code in pain and inflammation: lessons from bladder pain syndrome

Gheinani, Ali ; Burkhard, Fiona ; Monastyrskaya, Katia

In: Cellular and Molecular Life Sciences, 2013, vol. 70, no. 20, p. 3773-3789

Human Mast Cells and Mastocytosis: Harnessing MicroRNA Expression as a New Approach to Therapy?

Deho', Lorenzo ; Monticelli, Silvia

In: Archivum Immunologiae et Therapiae Experimentalis, 2010, vol. 58, no. 4, p. 279-286

AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension

Brock, Matthias ; Samillan, Victor J. ; Trenkmann, Michelle ; Schwarzwald, Colin ; Ulrich, Silvia ; Gay, Renate E. ; Gassmann, Max ; Ostergaard, Louise ; Gay, Steffen ; Speich, Rudolf ; Huber, Lars C.

In: European Heart Journal, 2014, vol. 35, no. 45, p. 3203-3211

Role of microRNAs in stem/progenitor cells and cardiovascular repair

Jakob, Philipp ; Landmesser, Ulf

In: Cardiovascular Research, 2012, vol. 93, no. 4, p. 614-622

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction

Barile, Lucio ; Lionetti, Vincenzo ; Cervio, Elisabetta ; Matteucci, Marco ; Gherghiceanu, Mihaela ; Popescu, Laurentiu M. ; Torre, Tiziano ; Siclari, Francesco ; Moccetti, Tiziano ; Vassalli, Giuseppe

In: Cardiovascular Research, 2014, vol. 103, no. 4, p. 530-541

A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction

Jaguszewski, Milosz ; Osipova, Julia ; Ghadri, Jelena-Rima ; Napp, Lars Christian ; Widera, Christian ; Franke, Jennifer ; Fijalkowski, Marcin ; Nowak, Radoslaw ; Fijalkowska, Marta ; Volkmann, Ingo ; Katus, Hugo A. ; Wollert, Kai C. ; Bauersachs, Johann ; Erne, Paul ; Lüscher, Thomas F. ; Thum, Thomas ; Templin, Christian

In: European Heart Journal, 2014, vol. 35, no. 15, p. 999-1006